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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T8441 Lerisetron

5-HT Receptor GPCR/G Protein; Neuroscience
Lerisetron 是5-HT3拮抗剂,与 5-HT3受体具有高亲和力(pKi:9.2)。它对尿烷麻醉大鼠的 5-HT 引发的反射性心率过缓具有抑制作用。
T28653 S-8510 free base

SB 737552,SB-737552,S8510,SB737552,S-8510,S 8510

S-8510 is a GABA-A receptor inverse agonist. S-8510 selectively potentiated pentylenetetrazol-induced convulsion without affecting minimal electroconvulsive shock- or strychnine-induced convulsion in ddY mice. S-8510 ameliorated memory impairment induced
T37585 Ensartinib

Ensartinib (X-396) is a potent and dual ALK/MET inhibitor with IC50s of <0.4 nM and 0.74 nM, respectively. The ability of Ensartinib (X-396) to inhibit the growth of different cancer cell lines harboring ALK fusions or point mutations is tested. Ensartinib is potent in H3122 lung cancer cells harboring EML4-ALK E13;A20 (IC50: 15nM). Ensartinib is also potent in H2228 lung cancer cells harboring EML4-ALK E6a/b; A20 (IC50: 45 nM). Furthermore, X-376 is potent in SUDHL-1 lymphoma cells harboring N...

化合物

Lerisetron
Cat.No: T8441
Synonym:
Target: 5-HT Receptor
S-8510 free base
Cat.No: T28653
Synonym: SB 737552,SB-737552,S8510,SB737552,S-8510,S 8510
Target:
Ensartinib
Cat.No: T37585
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TN4291 Isofuranodiene

IL Receptor; NOS Immunology/Inflammation
Isofuranodiene protects GalN/LPS-induced liver injury in SD rats, it may be a potential functional food ingredient for the prevention and treatment of liver diseases. Isofuranodiene has anticancer activity, by inhibiting the proliferation and inducing apo

天然产物

Isofuranodiene
Cat.No: TN4291
Synonym:
Target: IL Receptor, NOS
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