Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T70862 |
AMPK Activator SC4
|
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SC4 is a potent, direct AMPK activator. SC4 preferentially activates α2 complexes and stimulates skeletal muscle glucose uptake. | |||
T70860 |
Banoxantrone
AQ4N |
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Banoxantrone (AQ4N) 作为一种典型的缺氧选择性细胞毒素。Banoxantrone 可被还原为 AQ4,AQ4 是一种有效的拓扑异构酶 II 抑制剂。Banoxantrone 通过iNOS 依赖机制选择性地杀死缺氧细胞。Banoxantrone 显示出强大的细胞毒性和低氧选择性效应,且能被辐射增强。 | |||
T8985 |
NSC45586
|
Others | Others |
NSC45586 是一种蛋白磷酸酶 PHLPP 抑制剂,对 PHLPP1 和 PHLPP2 具有选择性。 | |||
T28206 |
NSC49652
NSC 49652,NSC-49652 |
Apoptosis | Apoptosis |
NSC49652 在神经元和黑色素瘤细胞中触发依赖于 p75NTR 和 JNK 活性的凋亡细胞死亡,并抑制黑色素瘤小鼠模型中的肿瘤生长。 | |||
T61116 |
NSC405640
|
||
NSC405640 is a highly effective compound that inhibits the interaction between MDM2 and p53 proteins. Furthermore, it can restore the structural integrity of p53 molecules affected by mutations. Notably, NSC405640 exhibits selectivity in inhibiting the growth of cell lines that possess the normal, unmutated form of the p53 protein [1]. | |||
T28205 |
NSC47924
NSC 47924,NSC-47924 |
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NSC47924 is a laminin receptor (LR) inhibitor. | |||
T34557 |
SC46275
SC 46275,SC-46275 |
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SC46275 is a bioactive chemical. |