Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12861 |
SB-277011
SB-277011A |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
SB-277011 (SB-277011A) 是多巴胺 D3 受体的特异性拮抗剂,对 D3 受体、D2 受体、5-HT1D 和 5-HT1B 的 pKi 值分别为 8.0、6.0、5.0 和 <5.2。 | |||
T12861L |
SB-277011 dihydrochloride
SB-277011A dihydrochloride |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
SB-277011 dihydrochloride is a potent, selective, orally bioavailable and brain penetrate antagonist of dopamine D3 receptor(pKis of 8.0, 6.0, <5.2 and 5.9 for D3, D2, 5-HT1B, and 5-HT1D receptors, respectively). |