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Cat. No. | Product Name | Target | Signaling Pathways |
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T13346L |
WQ3810 TFA
WQ3810 TFA(888032-58-4 Free base),KPI-10 TFA |
Antifungal | Microbiology/Virology |
WQ3810 TFA 是一种可口服的氟喹诺酮,具有抗菌活性,对结核分枝杆菌有抑制作用,抑制氧氟沙星耐药麻风分枝杆菌的 DNA 旋转酶活性。 | |||
T28760 |
Setafrastat
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Setafrastat is a vascular endothelial growth factor (VEGF) promotor and rotamase inhibitor. |
Cat. No. | Product Name | Species | Expression System |
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TMPJ-00971 |
PPIC Protein, Human, Recombinant (Trx & His)
PPIase C,Peptidyl-Prolyl Cis-Trans Isomerase C,PPIC,Cyclophi... |
Human | E. coli |
Cyclophilin C is an enzyme (EC 5.2.1.8) found in both prokaryotes and eukaryotes that interconverts the cis and trans isomers of peptide bonds with the amino acid proline. Proline has an unusually conformationally restrained peptide bond due to its cyclic structure with its side chain bonded to its secondary amine nitrogen. Most amino acids have a strong energetic preference for the trans peptide bond conformation due to steric hindrance, but prolines unusual structure stabilizes the cis form so... | |||
TMPJ-01389 |
PPIE Protein, Human, Recombinant (His)
Rotamase E,PPIE,Cyclophilin E,PPIase E,CYP33,Cyclop... |
Human | E. coli |
Peptidyl-prolyl cis-trans isomerase E, also known as Cyclophilin E, Cyclophilin-33, Rotamase E, CYP33, PPIE, is an enzyme which belongs to the cyclophilin-type PPIase family of PPIase E subfamily. PPIE found in all the examined tissues including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. PPIE contains one PPIase cyclophilin-type domain and one RRM (RNA recognition motif) domain. PPIE accelerates the folding of proteins. It catalyzes the cis-trans isomerization of ... | |||
TMPJ-00919 |
FKBP2 Protein, Human, Recombinant (His)
also named 13 kDa FK506-binding protein,FK506-binding protei... |
Human | HEK293 Cells |
Peptidyl-prolyl cis-trans isomerase FKBP2(FKBP2 for short), also named 13 kDa FK506-binding protein, FK506-binding protein 2, Immunophilin FKBP13, Rotamase, is a endoplasmic reticulum peripheral membrane protein. It contains 1 PPIase FKBP-type domain and belongs to the FKBP-type PPIase family, FKBP2 subfamily which takes part in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP2 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 an... | |||
TMPJ-00048 |
CYPA Protein, Mouse, Recombinant
SP18,PPIA,PPIase A,Peptidyl-prolyl cis-trans isomerase A,CYP... |
Mouse | E. coli |
Peptidyl-prolyl cis-trans isomerase A is a cytoplasm protein which belongs to the cyclophilin-type PPIase family and PPIase A subfamily. Cyclophilins(CyPs) are a family of proteins found in organisms ranging from prokaryotes to humans. These molecules exhibit peptidyl-prolyl isomerase activity, suggesting that they influence the conformation of proteins in cells. Cyclophilin A accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopep... | |||
TMPJ-01049 |
CYPA Protein, Human, Recombinant
Rotamase A,Peptidyl-prolyl cis-trans isomerase A,PP... |
Human | E. coli |
Peptidyl-prolyl cis-trans isomerase A is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds. Cyclophilin A regulate many biological processes, including intracellular signaling, transcription, inflammation, and apoptosis. Cyclophilin is also incorporated into many viruses, including HIV1, where it has been speculated to be involved in functions such as viral assembly and infectivity. The immunosuppressi... | |||
TMPJ-01396 |
PIN4 Protein, Human, Recombinant (His)
Peptidyl-prolyl cis-trans isomerase Pin4,Parvulin-14,Peptidy... |
Human | E. coli |
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4(PIN4) is a peptidyl-prolyl cis/trans isomerase (PPIase) which interacts with NIMA and is vital for cell cycle regulation. PIN4 has 2 different isoforms: PAR14 and PAR17. Furthermore, PIN4 protein binds to double-stranded DNA under physiological salt conditions. PIN4 is involved as a ribosomal RNA processing factor in ribosome biogenesis. The PAR14 binds to tightly bent AT-rich stretches of double-stranded DNA, but PAR17 binds to double-stran... | |||
TMPJ-01076 |
FKBP4 Protein, Human, Recombinant (His)
FKBP4,HSP-binding immunophilin,immunophilin FKBP52,FK506-bin... |
Human | E. coli |
FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. | |||
TMPJ-00676 |
PPIH Protein, Human, Recombinant (His)
Peptidyl-Prolyl Cis-Trans Isomerase H,Rotamase H,PP... |
Human | E. coli |
Peptidyl-Prolyl Cis-Trans Isomerase H (PPIH) belongs to the Cyclophilin-type PPIase family that accelerate the folding of proteins. PPIases can catalyze the cis-trans isomerization of Proline Imidic peptide bonds in oligopeptides. PPIH participates in pre-mRNA splicing. It is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. In addition, PPIH has PPIase activity and may play a role as a chaperone mediating the i... | |||
TMPJ-01090 |
PPID Protein, Human, Recombinant (His)
Cyclophilin-40,CYPD,Peptidyl-Prolyl Cis-Trans Isomerase D, |
Human | E. coli |
Peptidyl-Prolyl Cis-Trans Isomerase D (PPID) belongs to the cyclophilin-type PPIase family and PPIase D subfamily. PPID is widely expressed and it contains one PPIase cyclophilin-type domain and three TPR repeats. PPID catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. PPID can bind to the immunosuppressant cyclosporine A and is known that its overexpression suppresses the apoptosis in cancer cells. | |||
TMPJ-01068 |
FKBP25/FKBP3 Protein, Human, Recombinant (His)
25 kDa FKBP,FKBP-3,Peptidyl-prolyl cis-trans isomerase FKBP3... |
Human | E. coli |
FKBP25 contains 1 PPIase FKBP-type domain, belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a... |