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Cat. No.	Product Name	Target	Signaling Pathways
T63430	Rosuvastatin Sodium
	Rosuvastatin Sodium 是竞争性HMG-CoA 还原酶 (HMGCR) 抑制剂 (IC50: 11 nM)，能够有效阻断hERG 电流 (IC50: 195 nM)。Rosuvastatin Sodium 可以有效减少低密度脂蛋白 (LDL) 胆固醇，甘油三酯和 C- 反应蛋白水平。Rosuvastatin Sodium 能够减少成熟 hERG 的表达，并抑制及热休克蛋白 70 (Hsp70) 与 hERG 蛋白的相互作用。
T35718	N-desmethyl Rosuvastatin (sodium salt hydrate)
	N-desmethyl Rosuvastatin is an active metabolite of the HMG-CoA reductase inhibitor rosuvastatin .1,2N-desmethyl Rosuvastatin is formed when rosuvastatin undergoes demethylation, primarily by the cytochrome P450 (CYP) isoform CYP2C9 and to a lesser extent by CYP2C19 and CYP3A4.1 1.Macwan, J.S., Ionita, I.A., and Akhlaghi, F.A simple assay for the simultaneous determination of rosuvastatin acid, rosuvastatin-5S-lactone, and N-desmethyl rosuvastatin in human plasma using liquid chromatography-tand...
T12759	Rosuvastatin D6 Sodium	Others	Others
	Rosuvastatin D6 Sodium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM).
T12757	Rosuvastatin D3 Sodium	Others	Others
	Rosuvastatin D3 Sodium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM).