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Cat. No. | Product Name | Target | Signaling Pathways |
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T37168 |
Resolvin D1 methyl ester
Resolvin D1 methyl ester |
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Resolvin D1 is produced physiologically from the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase . It reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with an EC50 value of ~30 nM. RvD1 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracell... | |||
T35946 |
17(R)-Resolvin D1
Aspirin-triggered Resolvin D1,17(R)-Resolvin D1 |
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Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.[1] In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state.[2] Resolvin D1 is produced physiologically from the sequential oxygenation of DHA by 15- and 5-lipoxygenase.[1] 17(R)-RvD1 is an aspirin-triggered epimer of RvD1 that reduces human polymorphonuclear leukocyte (PMN) transendothelial migration, the ear... |
Cat. No. | Product Name | Target | Signaling Pathways |
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T13864 |
Resolvin D1
RvD1 |
Apoptosis | Apoptosis |
Resolvin D1 (RvD1) 是一种内源性促进炎症消解介质,可通过调节肌动蛋白聚合阻断促进炎症的中性粒细胞迁移,减少 TNF-α 介导的炎症在巨噬细胞中的作用,并增强巨噬细胞对凋亡细胞的吞噬作用。 |