5
1
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T60910 |
RSV-IN-4
|
||
RSV-IN-4 (Compound 2) 具有抗 RSV 活性,EC50值为11.76 μM。RSV-IN-4 是呼吸道合胞病毒 (RSV) 和甲流病毒 A (IAV) 的双重抑制剂。 | |||
T79220 |
RSV L-protein-IN-4
|
RSV | Microbiology/Virology |
RSVL-Protein-IN-4 (Compound C)为非竞争性RSV聚合酶抑制剂,IC50为0.88 μM。该化合物对RSV株显示出抗病毒活性,其EC50为0.25 μM。 | |||
T73253 |
EIDD-2749
4'-Fluorouridine,4'-FlU ; 4'-Fluorouridine,4'-FlU |
||
EIDD-2749 (4'-Fluorouridine) 是一种口服有效的RdRp 抑制剂。EIDD-2749 能有效抑制RSV 和SARS-CoV-2的复制。EIDD-2749 还表现出抗HCV 和淋巴细胞性脉络丛脑膜炎病毒 (LCMV) 的活性。EIDD-2749 是一种很有潜力的COVID-19口服治疗候选剂,也适用于其他 RNA 病毒的研究。 | |||
T36440 |
GS-441524 tris-isobutyryl ester
|
||
GS-441524tris-isobutyryl ester is a prodrug form of the antiviral nucleoside analog and remdesivir metabolite GS-441524 .1It reduces the cytopathic effect of respiratory syncytial virus (RSV) in infected HEp-2 cells with an EC50value of 0.26 μM. 1.Mackman, R.L., Hui, H.C., Perron, M., et al.Prodrugs of a 1’-CN-4-aza-7,9-dideazaadenosine C-nucleoside leading to the discovery of remdesivir (GS-5734) as a potent inhibitor of respiratory syncytial virus with efficacy in the african green monkey mode... | |||
T38297 |
Ribavirin-13C5
Ribavirin-13C5 |
||
Ribavirin-13C5is intended for use as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin is an antiviral guanosine nucleoside analog.1,2Upon entry into cells, ribavirin is metabolized to an active triphosphate form that induces viral RNA chain termination and inhibits viral polymerases. It reduces replication in a panel of seven RNA and four DNA viruses in Vero cells (EC50s = 2-95 μg/ml).3Ribavirin also reduces replication of severe acute respiratory syndrome coro... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN3048 |
4-Methoxycinnamaldehyde
p-Methoxycinnamaldehyde |
RSV | Microbiology/Virology |
4-Methoxycinnamaldehyde (p-Methoxycinnamaldehyde) 是 Agastache rugosa 的一种活性成分。4-Methoxycinnamaldehyde 对人喉癌细胞系中的呼吸道合胞病毒 (RSV) 具有细胞保护活性,有助于控制 RSV 感染诱发的疾病,IC50 约为 0.055 μg/mL。 |