Cat. No. | Product Name | Target | Signaling Pathways |
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T60340 |
ROS 234
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ROS 234 is a highly effective H3 antagonist, demonstrating a strong binding affinity (pK B) of 9.46 for the Guinea-pig ileum H3 receptor and a pKi of 8.90 for the Rat cerebral cortex H3 receptor. Additionally, it exhibits an ex vivo ED50 of 19.12 mg/kg (ip) in the Rat cerebral cortex. It should be noted that ROS 234 demonstrates limited central access, as reported in [1] and [2]. | |||
T12756 | ROS 234 dioxalate | Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
ROS 234 dioxalate is a potent antagonist of H3(pKB of 9.46 for Guinea-pig ileum H3-receptor) |