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Cat. No. Product Name Target Signaling Pathways
T13320L VU591

Potassium Channel Membrane transporter/Ion channel
VU591 是选择性的肾外髓钾通道抑制剂,IC50为 0.24 μM。
T13320 VU591 hydrochloride

Potassium Channel Membrane transporter/Ion channel
VU591 hydrochloride 是选择性的肾外髓钾通道抑制剂,IC50为 0.24 μM。
T70634 Psycholeine

Psycholeine is isolated from the tropical plant Psychotria oleoides; exhibits somatostatin antagonistic activity on growth hormone secretion.
T23516 VU590

Potassium Channel Membrane transporter/Ion channel
VU590 是一种具有高效性和中等选择性的肾外髓质钾 ROMK (Kir1.1) 抑制剂。VU590 抑制 Kir7.1,可调节子宫肌层收缩力和黑皮质素信号传导。
T24623 PF-06807656

PF 06807656

PF-06807656 is insensitive to the introduction of the N171D mutation in the ROMK conduction pore that greatly diminishes the activity of other small-molecule inhibitors. PF-06807656 is an effective ROMK inhibitor (Tl+ flux IC50 = 160 nM).
T12066 MK-7145

Others Others
MK-7145 is an inhibitor of ROMK(IC50 of 0.045 μM).
T70636 XAN35021

XAN35021, also known as ROMK inhibitor 25, or ROMK-IN-25, is a potent and selective ROMK inhibitor with improved pharmacokinetic properties. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
T62760 ROMK-IN-32

ROMK-IN-32 是一种肾外髓质钾通道 (ROMK) 抑制剂 (IC50: 35 nM),也能够抑制 hERG (IC50: 22 μM)。
T62544 MK-8153

MK-8153 是一种选择性的、有效的、口服具有活力的肾外髓质钾通道 (ROMK) 抑制剂,作用于 ROMK EP (IC50: 5 μM) 和 hERG EP (IC50: 34 μM)。MK-8153 能够用作利尿剂。

化合物

VU591
Cat.No: T13320L
Synonym:
Target: Potassium Channel
VU591 hydrochloride
Cat.No: T13320
Synonym:
Target: Potassium Channel
Psycholeine
Cat.No: T70634
Synonym:
Target:
VU590
Cat.No: T23516
Synonym:
Target: Potassium Channel
PF-06807656
Cat.No: T24623
Synonym: PF 06807656
Target:
MK-7145
Cat.No: T12066
Synonym:
Target: Others
XAN35021
Cat.No: T70636
Synonym:
Target:
ROMK-IN-32
Cat.No: T62760
Synonym:
Target:
MK-8153
Cat.No: T62544
Synonym:
Target:
TargetMol Loading
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