Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6788 |
Bitopertin
Paliflutine,比拓喷丁,RO4917838,RG1678,比托派汀 |
GlyT | Neuroscience |
Bitopertin (Paliflutine) 是一种有效的甘氨酸转运蛋白 1 (GlyT1) 抑制剂,对人 hGlyT1b 的 Ki 为 8.1 nM。 | |||
T10552 |
Bitopertin (R enantiomer)
RO4917838 (R enantiomer),RG1678 (R enantiomer),Bitopertin R enantiomer |
GlyT | Neuroscience |
Bitopertin R enantiomer (RG1678 R enantiomer) is the R-enantiomer of Bitopertin. Bitopertin is a noncompetitive glycine reuptake inhibitor and inhibits glycine uptake at human GlyT1 (IC50: 25 nM). |