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抑制剂 & 化合物

天然产物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TP1971	Pseudo RACK1
	Activator of protein kinase C; attached to cell permeabilization Antennapedia domain vector peptide. Consists of peptide derived from the C2 domain of PKC β linked by a disulfide bridge to the Antennapedia domain vector peptide. The Antennapedia peptide i
T9500	M435-1279	E1/E2/E3 Enzyme	Ubiquitination
	M435-1279 是有效的 UBE2T 抑制剂。M435-1279 可以阻断 UBE2T 介导的 RACK1 降解，从而导致抑制 Wnt/β-catenin 信号通路的过度激活。
T13810	Palmitoylcarnitine chloride Palmitoyl DL-carnitine chloride	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	Palmitoylcarnitine chloride (Palmitoyl DL-carnitine chloride) 是一种线粒体脂肪酸氧化中间体，可介导脂质内心脏保护。Palmitoylcarnitine chloride 通过消耗谷胱甘肽来消除结直肠癌细胞的存活，诱导癌细胞死亡，调节蛋白激酶 C βII 与其受体 RACK1 之间的相互作用。
T76444	Protein Kinase C (660-673)
	Protein Kinase C (660-673) (PKC βII (660-673)) 是具有 RACK1结合亲和力的 PKCβII V5 肽。
T81571	PACAP (1-38) free acid TFA
	PACAP (1-38) free acid TFA，一种内源性神经肽，能有效促进胃窦运动，增强体液蛋白分泌，同时抑制胃泌素释放。此外，它刺激血管活性肠肽、胃泌素释放肽和P物质的释放，并通过RACK1增强N-甲基-D-天门冬氨酸受体功能及脑源性神经营养因子表达。
T81572	PACAP (1-38) free acid
	PACAP (1-38) free acid 是一种具有多重生物功能的内源性神经肽，主要作用包括刺激胃窦运动、增进体液蛋白分泌、抑制胃泌素分泌，以及促进血管活性肠肽、胃泌素释放肽和P 物质的释放。此外，PACAP (1-38) free acid 通过与RACK1互作，可以增强N-甲基-D-天门冬氨酸受体的功能并促进脑源性神经营养因子的表达。

化合物

Target: E1/E2/E3 Enzyme

Palmitoylcarnitine chloride

Cat.No: T13810

Synonym: Palmitoyl DL-carnitine chloride

Target: PKC

Protein Kinase C (660-673)

Cat.No: T76444

Synonym:

Target:

PACAP (1-38) free acid TFA

Cat.No: T81571

Synonym:

Target:

PACAP (1-38) free acid

Cat.No: T81572

Synonym:

Target:

Cat. No.	Product Name	Target	Signaling Pathways
TN6238	Harringtonolide
	Harringtonolide 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6238，CAS号为 64761-48-4。

天然产物

Species：

Expression System：

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Cat. No.	Product Name	Species	Expression System
TMPY-02761	Rack1 Protein, Human, Recombinant (His & MBP) PIG21,Gnb2-rs1,H12.3,RACK	Human	E. coli
	The scaffolding protein, Rack1, is a seven-WD-domain-containing protein that has been implicated in binding to integrin beta subunit cytoplasmic domains and to members of two kinase families (src and protein kinase C, PKC) that mediate integrin bidirectional signaling.Rack1 may link protein kinase C directly to integrins and participate in the regulation of integrin functions.Rack1 regulates the localization of an essential PCP protein and acts as a molecular switch to promote PCP signaling.
TMPH-01581	KRT1 Protein, Human, Recombinant (His)	Human	E. coli
	May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK. KRT1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 69.9 kDa and the accession number is P04264.