Cat. No. | Product Name | Target | Signaling Pathways |
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T71400 |
Quizartinib HCl
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Quizartinib, also know as AC220 and AC010220, is an orally available FLT3 / STK1 inhibitor with potential antineoplastic activity. Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III receptor tyrosine kinases, including FMS-related tyrosine kinase 3 (FLT3/STK1), colony-stimulating factor 1 receptor (CSF1R/FMS), stem cell factor receptor (SCFR/KIT), and platelet derived growth factor receptors (PDGFRs), resulting in inhibition of ligand-independent leukemic cell pro... | |||
T71399 |
Plogosertib
CYC140 |
PLK | Cell Cycle/Checkpoint |
Plogosertib (CYC140) 是一种具有口服活性、选择性、高效性和 ATP 竞争性的 PLK1 抑制剂 ,IC50 值为 3 nM。Plogosertib 具有抗增殖和抗癌活性,可用于研究实体瘤和血液肿瘤。 |