Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0805 |
Quinapril hydrochloride
CI-906,PD-109452-2,盐酸喹那普利,Quinapril HCl |
RAAS | Endocrinology/Hormones |
Quinapril hydrochloride (PD-109452-2) 是一种血管紧张素转化酶(ACE) 抑制剂的原药。 | |||
T71065 |
Quinapril-d5
|
||
Quinapril-d5 is intended for use as an internal standard for the quantification of quinapril by GC- or LC-MS. Quinapril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor quinaprilat. In vivo, quinapril reduces mean arterial pressure in renal hypertensive and spontaneously hypertensive rats. It inhibits angiotensin I-induced pressor responses in normotensive rats and dogs. Quinapril prevents left ventricular heart failure in CHF 14.6 cardiomyopathic hamsters. Formulations con... | |||
T19631 |
PD 109488
PD-109488,Quinapril Diketopiperazine,PD109488 |
||
PD 109488 is a metabolite of quinapril and is a derivative of Quinapril that acts as an ACE inhibitor. Inhibition of ACE prevents the conversion of signaling peptide angiotensin I into angiotensin II, which acts as a potent vasoconstrictor. Reduced levels of angiotensin II also reduces the amount of aldosterone that is expressed due to RAAS signaling. | |||
T71063 |
Tolytoxin
|
||
Tolytoxin is a cytostatic, antifungal macrolide produced by blue-green algae of the genus Scytonema, is a potent, reversible inhibitor of cytokinesis in cultured mammalian cells | |||
T28485 |
Quinaprilat hydrate
Quinaprilat,CI-928,CI 928,BRN 5653070 |
||
Quinaprilat is the active metabolite of quinapril, an angiotensin-converting enzyme inhibitor used in the treatment of congestive heart failure and hypertension. | |||
T21049 |
Quinaprilat
CI-928,CI928,CI 928 |
||
Quinaprilat inhibits angiotensin converting enzyme. | |||
T28309 |
PD 113413
PD-113413,PD113413 |
||
PD 113413 is a metabolite of quinapril, an angiotensin-converting enzyme inhibitor for the treatment of hypertension and congestive heart failure. |