Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-01308 |
ITPase Protein, Human, Recombinant (His)
Nucleoside-Triphosphate Diphosphatase,Nucleoside-Triphosphat... |
Human | E. coli |
Inosine Triphosphate Pyrophosphatase (ITPase) is a cytoplasmic enzyme that belongs to the HAM1 NTPase family. ITPase hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP) and deoxyinosine triphosphate (dITP) to the monophosphate nucleotide (IMP) and diphosphate. The ITPase enzyme acts as a homodimer and does not distinguish between the deoxy- and ribose forms. ITPase probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation... |