Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7513 |
Protease-Activated Receptor-2, amide
蛋白酶活化的受体-2,酰胺,SLIGKV-NH2,H-丝氨酰亮氨酰异亮氨酰甘氨酰赖氨酰缬氨酰NH2 |
Protease-activated Receptor | GPCR/G Protein |
Protease-Activated Receptor-2, amide (SLIGKV-NH2) 是 PAR2 的激动剂,IC50为 10.4 M。 | |||
TP1378 |
2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base)
2-Furoyl-LIGRLO-amide |
Protease-activated Receptor | GPCR/G Protein |
2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base) 是一种有效的选择性蛋白酶激活受体 2 (PAR2) 激动剂。 | |||
T35955 |
PAR2 (1-6) amide (human) (trifluoroacetate salt)
PAR2 (1-6) amide (human) (trifluoroacetate salt) |
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PAR2 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR2 and residues 37-42 of the full-length sequence.1It binds to NCTC 2544 cells expressing human PAR2 (Ki= 9.64 μM in a radioligand binding assay) and induces calcium mobilization in the same cells (EC50= 0.075 μM).2PAR2 (1-6) amide (100 μM) reduces colony formation of A549 lung cancer cells.1It induces superoxide prod... |