Cat. No. | Product Name | Target | Signaling Pathways |
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T39804 |
Pomalidomide-PEG3-azide
Pomalidomide-PEG3-azide |
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Pomalidomide-PEG3-azide is a chemically synthesized conjugate comprised of a cereblon ligand based on Pomalidomide, an E3 ligase ligand-linker, and a 3-unit PEG linker. This conjugate is specifically designed for use in PROTAC technology. | |||
T39806 |
Pomalidomide 4'-PEG3-azide
Pomalidomide 4'-PEG3-azide |
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Pomalidomide 4'-PEG3-azide is a chemically synthesized conjugate consisting of an E3 ligase ligand-linker conjugate that incorporates the cereblon ligand derived from Pomalidomide, along with a linker. This compound, Pomalidomide 4'-PEG3-azide, is utilized in the synthesis of iRucaparib-TP3 (Compound 3). iRucaparib-TP3, developed through the PROTAC strategy, is an effective degrader of PARP1, derived from Rucaparib. |