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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T12245 Nosantine racemate

诺次黄嘌呤外消旋体,NPT-15392 racemate

IL Receptor Immunology/Inflammation
Nosantine racemate is the racemate of Nosantine which is a IL-2 inducer or enhancer of IL-2 induction by phytohemagglutinin (PHA).
T37276 2,5-Deoxyfructosazine (hydrochloride)

2,5-Deoxyfructosazine is a pyrazine derivative that can be found in cured tobacco and is used as a flavoring agent in the food and tobacco industry. Pyrazines, including 2,5-deoxyfructosazine, can be produced either by pyrolytic decomposition of natural compounds or by the reaction of sugars with alcoholic ammonia. 2,5-Deoxyfructosazine is also formed by the breakdown of D-glucosamine at neutral pH. Like glucosamine, 2,5-deoxyfructosazine has DNA strand breakage activity and strongly inhibits IL...
T68321 AS1940477

AS1940477 is p38 MAPK inhibitor. AS1940477 inhibited the enzymatic activity of recombinant p38α and β isoforms but showed no effect against other 100 protein kinases including p38γ and δ isoforms. In human peripheral blood mononuclear cells, AS1940477 inhibited lipopolysaccharide (LPS)- or phytohemagglutinin A (PHA)-induced production of proinflammatory cytokines, including TNFα, IL-1β, and IL-6 at low concentrations (LPS/TNFα, IC(50)=0.45n M; PHA/TNFα, IC(50)=0.40 nM). In addition, equivalent c...

化合物

Nosantine racemate
Cat.No: T12245
Synonym: 诺次黄嘌呤外消旋体,NPT-15392 racemate
Target: IL Receptor
2,5-Deoxyfructosazine (hydrochloride)
Cat.No: T37276
Synonym:
Target:
AS1940477
Cat.No: T68321
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T13818 Phytohemagglutinin

PHA-M,植物血球凝集素,PHA,植物血凝素

Apoptosis Apoptosis
Phytohemagglutinin (PHA-M) 是一种普通豆菜豆的主要种子凝集素,聚集在子叶的薄壁细胞中。它是一种 T 细胞激活剂,能够刺激人单核白细胞,可诱导 ChAT mRNA 表达,增强 ACh 合成。
T78491 Phytohemagglutinin P

PHA-P

Phytohemagglutinin P(PHA-P)是一类植物凝集素,以选择性方式激活血源性或淋巴样单核细胞的有丝分裂。

天然产物

Phytohemagglutinin
Cat.No: T13818
Synonym: PHA-M,植物血球凝集素,PHA,植物血凝素
Target: Apoptosis
Phytohemagglutinin P
Cat.No: T78491
Synonym: PHA-P
Target:
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