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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T39704 |
KSC-34
|
Others | Others |
KSC-34 是蛋白二硫异构酶 A1(PDIA1)的共价修饰剂,是一种针对 PDIA1 的 a 位点的选择性抑制剂,以时间依赖的方式抑制PDIA1 还原酶活性,可用于研究淀粉样蛋白异常引起的疾病。 | |||
T11141 |
E64FC26
|
Others | Others |
E64FC26 是一种有效的蛋白质二硫键异构酶 (PDI) 家族泛抑制剂,具有抗肿瘤活性,抑制 PDIA1、PDIA3、PDIA4、TXNDC5 和 PDIA6,可用于研究多发性骨髓瘤和胰腺癌。 | |||
T39812 |
(E/Z)-E64FC26
(E/Z)-E64FC26 |
||
(E/Z)-E64FC26 is a mixture complex comprising E-E64FC26 and Z-E64FC26. E-E64FC26 is a highly potent pan-inhibitor of the protein disulfide isomerase (PDI) family, with IC50 values of 1.9, 20.9, 25.9, 16.3, and 25.4 μM against PDIA1, PDIA3, PDIA4, TXNDC5, and PDIA6, respectively. Furthermore, E64FC26 demonstrates anti-myeloma activity. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01012 |
P4HB Protein, Human, Recombinant (His)
DSI,prolyl 4-hydroxylase, β polypeptide,PDIA1 |
Human | HEK293 Cells |
P4HB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.4 kDa and the accession number is A0A024R8S5. | |||
TMPY-01795 |
P4HB Protein, Mouse, Recombinant (His)
ERp59,Pdia1,prolyl 4-hydroxylase, beta pol... |
Mouse | HEK293 Cells |
P4HB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.2 kDa and the accession number is P09103. |