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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6750 |
Opaganib
ABC294640 |
S1P Receptor | GPCR/G Protein |
Opaganib (ABC294640) 是选择性和竞争性的鞘氨醇激酶 2 (SK2) 抑制剂,Ki 为 9.8 μM。 | |||
T71301 | Opaganib HCl | ||
ABC294640, also known as Opaganib, is an orally available, aryladamantane compound and selective inhibitor of sphingosine kinase-2 (SK2) with potential antineoplastic activity. Upon administration, ABC294640 competitively binds to and inhibits SK2, thereby preventing the phosphorylation of the pro-apoptotic amino alcohol sphingosine to sphingosine 1-phosphate (S1P), the lipid mediator that is pro-survival and critical for immunomodulation. This may eventually lead to the induction of apoptosis a... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01276 |
Peroxiredoxin 1 Protein, Human, Recombinant (His)
PAGA,peroxiredoxin 1,NKEFA,MSP23,PAG,TDPX2,PAGB,PRX... |
Human | E. coli |
Peroxiredoxin 1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.9 kDa and the accession number is A0A384NPQ2. | |||
TMPY-02372 |
Peroxiredoxin 1 Protein, Mouse, Recombinant (His)
PAG,OSF-3,OSF3,Paga,PRDX1,Tdpx2,PrxI,TDX2,TPxA,prx1... |
Mouse | E. coli |
Peroxiredoxin 1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.5 kDa and the accession number is P35700. |