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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP2222 |
APTSTAT3-9R
|
Others | Others |
APTSTAT3-9R-9R is a STAT3 inhibitor (Ki: 231 nmol/L). STAT3 has been reported to promote the proliferation, survival, metastasis, immune escape, as well as drug resistance of cancer cells, making it a promising target for various diseases. However, though | |||
TP2222L |
APTSTAT3-9R acetate
|
STAT | JAK/STAT signaling; Stem Cells |
APTSTAT3-9R acetate 是一种特异性肽结合 STAT3,具有抗增殖和抗肿瘤活性。 APTSTAT3-9R acetate 并通过特异性阻断 STAT3 磷酸化来抑制 STAT3 活化和下游信号传导。 | |||
T23078 |
NPE-caged-HPTS
|
Others | Others |
Caged fluorescent pH indicator |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03452 |
PTS Protein, Human, Recombinant (His)
PTPS,PTS,6-pyruvoyltetrahydropterin synthase |
Human | E. coli |
PTS(6-pyruvoyltetrahydropterin synthase) belongs to the PTPS family. It catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia.... |