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Targets Recommended: Phosphatase

1

抑制剂 & 化合物

4

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T60396 JMS-053

Phosphatase Metabolism
JMS-053 是一种具有有效性和选择性的磷酸酶 DUSP3 抑制剂, 抑制 PTP4A3、 PTP4A1 、 PTP4A2 和 CDC25B,抑制癌细胞迁移和球体生长,避免血管内皮生长因子或脂多糖对微血管内皮屏障功能的破坏。

化合物

JMS-053
Cat.No: T60396
Synonym:
Target: Phosphatase
Cat. No. Product Name Species Expression System
TMPY-02386 PTP4A2 Protein, Human, Recombinant (GST)

HNMT-S2,PRL-2,HNMT-S1,protein tyrosine phosphatase type IVA,...

Human E. coli
PRL-2 (Protein-tyrosine phosphatase of regenerating liver 2), also known as PTP4A2 (Protein tyrosine phosphatase type IVA, member 2), is a member of PTP family and has an important function in controlling cell growth. PRL-2 phosphatases may be multifunctional enzymes with diverse roles in a variety of tissue and cell types. The phosphatase of regenerating liver (PRL) family, comprising PRL-1, PRL-2 and PRL-3, is a group of prenylated phosphatases that are candidate cancer biomarkers and therapeu...
TMPJ-00053 PRL-2 Protein, Human, Recombinant (His)

HU-PP-1,Protein tyrosine phosphatase type IVA 2,OV-1,PTP...

Human E. coli
PTP4A2, also known as PRL2 or PTPCAAX2, is short for Protein tyrosine phosphatase type IVA 2. This protein exists in cell membrane, cytoplasm,endosome and membrane. PTP4A2 is often farnesylated during post-translational modification. Farnesylation is required for membrane targeting and for interaction with RABGGTB. The unfarnesylated forms are redirected to the nucleus and cytosol. It can stimulate progression from G1 into S phase during mitosis and promotes tumors. It also inhibits geranylgeran...
TMPK-00742 PRL-3/PTP4A3 Protein, Human, Recombinant (His)

PRL-R,PRLR,PRL3,PTP4A3,PRL-3

Human E. coli
Phosphatases of regenerating liver (PRL-1, PRL-2, and PRL-3, also known as PTP4A1, PTP4A2, and PTP4A3) control magnesium homeostasis through an association with the CNNM magnesium transport regulators. PTP4A3 (PRL-3) plays an important role in the tumorigenesis and metastasis of multiple tumors.
TMPK-01132 PRL-1/PTP4A1 Protein, Human, Recombinant (His)

PTPCAAX1,PRL1,PRL-1,PTP(CAAXI),PTP

Human E. coli
Phosphatases of regenerating liver (PRL-1, PRL-2, and PRL-3, also known as PTP4A1, PTP4A2, and PTP4A3) control magnesium homeostasis through an association with the CNNM magnesium transport regulators. PRL-1 (PTP4A1) is a key molecule that activates tyrosine phosphorylation, which is important for cancer progression and metastasis.

重组蛋白

PTP4A2 Protein, Human, Recombinant (GST)
Cat.No: TMPY-02386
Species: Human
Expression System: E. coli
PRL-2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00053
Species: Human
Expression System: E. coli
PRL-3/PTP4A3 Protein, Human, Recombinant (His)
Cat.No: TMPK-00742
Species: Human
Expression System: E. coli
PRL-1/PTP4A1 Protein, Human, Recombinant (His)
Cat.No: TMPK-01132
Species: Human
Expression System: E. coli
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