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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T82696 Cofetuzumab

PF-06523435,hu24

Cofetuzumab (PF-06523435)为针对PTK7的人源化IgG1-κ亚型单克隆抗体,常在CHO(中国仓鼠卵巢)细胞表达体系中生产。

化合物

Cofetuzumab
Cat.No: T82696
Synonym: PF-06523435,hu24
Target:
Cat. No. Product Name Species Expression System
TMPY-06249 CCK4/PTK7 Protein, Human, Recombinant (His)

CCK4,PTK7

Human HEK293 Cells
CCK4/PTK7 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.1 kDa and the accession number is Q13308-1.
TMPK-01080 PTK7/CCK4 Protein, Mouse, Recombinant (His)

PTK7,CCK-4

Mouse HEK293 Cells
Protein Tyrosine Kinase 7 (PTK7) is as a critical regulator of canonical and non-canonical Wnt-signaling during embryonic development and cancer cell formation. Disrupting PTK7 activity perturbs vertebrate nervous system development, and also promotes human cancer formation. Observations in different model systems suggest a complex cross-talk between PTK7 protein and Wnt signaling. PTK7/CCK4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted mo...
TMPK-00520 PTK7/CCK4 Protein, Cynomolgus, Recombinant (His)

PTK7,CCK-4

Cynomolgus HEK293 Cells
Protein Tyrosine Kinase 7 (PTK7) is as a critical regulator of canonical and non-canonical Wnt-signaling during embryonic development and cancer cell formation. Disrupting PTK7 activity perturbs vertebrate nervous system development, and also promotes human cancer formation. Observations in different model systems suggest a complex cross-talk between PTK7 protein and Wnt signaling. PTK7/CCK4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predict...
TMPY-06250 CCK4/PTK7 Protein, Cynomolgus, Rhesus, Recombinant (His)

Cynomolgus,Rhesus HEK293 Cells
CCK4/PTK7 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.1 kDa and the accession number is XP_005552998.1&NP_001248508.1.
TMPH-00010 MMP-14 Protein, Human, Recombinant (His & SUMO)

Human E. coli
Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. Cleaves ADGRB1 to...

重组蛋白

CCK4/PTK7 Protein, Human, Recombinant (His)
Cat.No: TMPY-06249
Species: Human
Expression System: HEK293 Cells
PTK7/CCK4 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01080
Species: Mouse
Expression System: HEK293 Cells
PTK7/CCK4 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00520
Species: Cynomolgus
Expression System: HEK293 Cells
CCK4/PTK7 Protein, Cynomolgus, Rhesus, Recombinant (His)
Cat.No: TMPY-06250
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
MMP-14 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-00010
Species: Human
Expression System: E. coli
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