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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T82696 |
Cofetuzumab
PF-06523435,hu24 |
||
Cofetuzumab (PF-06523435)为针对PTK7的人源化IgG1-κ亚型单克隆抗体,常在CHO(中国仓鼠卵巢)细胞表达体系中生产。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-06249 |
CCK4/PTK7 Protein, Human, Recombinant (His)
CCK4,PTK7 |
Human | HEK293 Cells |
CCK4/PTK7 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.1 kDa and the accession number is Q13308-1. | |||
TMPK-01080 |
PTK7/CCK4 Protein, Mouse, Recombinant (His)
PTK7,CCK-4 |
Mouse | HEK293 Cells |
Protein Tyrosine Kinase 7 (PTK7) is as a critical regulator of canonical and non-canonical Wnt-signaling during embryonic development and cancer cell formation. Disrupting PTK7 activity perturbs vertebrate nervous system development, and also promotes human cancer formation. Observations in different model systems suggest a complex cross-talk between PTK7 protein and Wnt signaling. PTK7/CCK4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted mo... | |||
TMPK-00520 |
PTK7/CCK4 Protein, Cynomolgus, Recombinant (His)
PTK7,CCK-4 |
Cynomolgus | HEK293 Cells |
Protein Tyrosine Kinase 7 (PTK7) is as a critical regulator of canonical and non-canonical Wnt-signaling during embryonic development and cancer cell formation. Disrupting PTK7 activity perturbs vertebrate nervous system development, and also promotes human cancer formation. Observations in different model systems suggest a complex cross-talk between PTK7 protein and Wnt signaling. PTK7/CCK4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predict... | |||
TMPY-06250 |
CCK4/PTK7 Protein, Cynomolgus, Rhesus, Recombinant (His)
|
Cynomolgus,Rhesus | HEK293 Cells |
CCK4/PTK7 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.1 kDa and the accession number is XP_005552998.1&NP_001248508.1. | |||
TMPH-00010 |
MMP-14 Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. Cleaves ADGRB1 to... |