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Cat. No. Product Name Target Signaling Pathways
T11975 PROTAC Mcl1 degrader-1

BCL Apoptosis
PROTAC Mcl1 degrader-1 induces the ubiquitination and proteasomal degradation of Mcl-1 by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1 inhibitor S1-6 with μM-range affinity. PROTAC Mcl1 degrader-1, a proteolysis targeting chimera (PROTAC), is a potently and selectively Mcl-1 inhibitor with an IC50 of 0.78 μM.

化合物

PROTAC Mcl1 degrader-1
Cat.No: T11975
Synonym:
Target: BCL
TargetMol Loading
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