Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T18607 |
PROTAC ER Degrader-3
|
Others | Others |
PROTAC ER Degrader-3, an intermediate for the synthesis of PAC, specifically compound LP2. PAC serves as the linker for ADCs and PROTACs that are conjugated to an antibody. Notably, when PAC is conjugated to an antibody, it exhibits enhanced degradation of estrogen receptor-alpha (ERα) compared to PROTAC alone [1]. |