Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T17728 |
PROTAC CDK9 degrader-2
|
Others | Others |
PROTAC CDK9 degrader-2 (compounds 11c) is a potent and selective CDK9 degrader based on PROTAC, with an IC50 of 17 μM in MCF-7 cell lines. Natural product Wogonin binds ubiquitin E3 ligase cereblon (CRBN) via a linker to form PROTAC[1]. | |||
T79904 |
PROTAC CDK9/CycT1 Degrader-2
|
CDK | Cell Cycle/Checkpoint |
PROTACCDK9/CycT1 Degrader-2 对CDK9表现出较高的抑制效能,具有一个IC50值为45 nM。 | |||
T10742 |
CDK9-IN-10
|
CDK | Cell Cycle/Checkpoint |
CDK9-IN-10 是一种有效的 CDK9 抑制剂。CDK9-IN-10 是 PROTAC CDK9 degrader-2 的配体。 |