Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12552 |
PROTAC CDK2/9 Degrader-1
|
CDK; PROTACs | Cell Cycle/Checkpoint; PROTAC |
PROTAC CDK2/9 Degrader-1 is a potent CDK2 and CDK9 dual degrader(DC50 of 62 nM and 33 nM). | |||
T18805 | Thalidomide-C2-amido-C2-COOH | Others | Others |
Thalidomide-C2-amido-C2-COOH is a compound that includes a CRBN ligand for the E3 ubiquitin ligase, as well as a linker. It is utilized in the development of PROTAC CDK2/9 Degrader-1[1]. | |||
T18484 |
NH2-C2-amido-C2-Boc
|
Others | Others |
NH2-C2-amido-C2-Boc is an alkyl/ether-based PROTAC linker employed in the synthesis of various PROTACs, including the PROTAC CDK2/9 Degrader-1[1]. NH2-C5-NH-Boc can also serve as a suitable precursor for the synthesis of these PROTACs. |