Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T77975 |
PROTAC BRD9 Degrader-6
|
Epigenetic Reader Domain | Chromatin/Epigenetic |
PROTACBRD9Degrader-6,作为BRD9降解剂,表现出高效率(IC50=0.13 nM),主要应用于BAF复合物相关疾病的研究领域。 | |||
T39524 |
Thalidomide-NH-PEG2-C2-NH-Boc
Thalidomide-NH-PEG2-C2-NH-Boc |
||
Thalidomide-NH-PEG2-C2-NH-Boc, a synthesized E3 ligase ligand-linker conjugate, combines the cereblon-targeting Thalidomide ligand with a PEG linker for the synthesis of dBRD9 (compound 6). This selective BRD9 probe PROTAC degrader is utilized in researching BAF complex biology. |