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Cat. No. Product Name Target Signaling Pathways
T13833 PROTAC BRD4 Degrader-1

Epigenetic Reader Domain Chromatin/Epigenetic
PROTAC BRD4 Degrader-1 is an efficacious degrader of BRD4(BRD4 BD1,IC50 of 41.8 nM).
T18598 PROTAC BRD2/BRD4 degrader-1

Others Others
PROTAC BRD2/BRD4 degrader-1 (compound 15) serves as a potent, selective degrader of BET proteins BRD4 and BRD2, achieving rapid, reversible, and unexpectedly selective elimination of BRD4 and BRD2 compared to BRD3. Its efficacy in suppressing solid tumors manifest with minimal cytotoxic effects. This compound comprises a BET inhibitor, a connecting linker, and thalidomide as the ligand for cereblon (CRBN)/cullin 4A[1].

化合物

PROTAC BRD4 Degrader-1
Cat.No: T13833
Synonym:
Target: Epigenetic Reader Domain
PROTAC BRD2/BRD4 degrader-1
Cat.No: T18598
Synonym:
Target: Others
TargetMol Loading
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