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Targets Recommended: p38 MAPK

1

抑制剂 & 化合物

3

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T29071 UR13870

Org 48762-0,POLB 001,UR-13870,UR 13870

p38 MAPK MAPK
UR-13870 (Org 48762-0) 是一种具有口服活性和选择性的 p38 丝裂原活化蛋白激酶(MAPK)抑制剂,可防止小鼠胶原诱导的关节炎中的骨损伤。

化合物

UR13870
Cat.No: T29071
Synonym: Org 48762-0,POLB 001,UR-13870,UR 13870
Target: p38 MAPK
Cat. No. Product Name Species Expression System
TMPJ-00792 DNA PolymeraseBeta Protein, Human, Recombinant (His)

DNA Polymeraseβ,POLB,DNA Polymerase Beta,DNA Polyme...

Human E. coli
Human DNA polymerase β is constitutively expressed in cells. It fills in gaps in DNA that are formed following base excision repair. Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. It conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a proce...
TMPH-00613 DNA polymerase II Protein, E. coli, Recombinant (His & Myc)

DNA polymerase II,polB,dinA,Pol II

E. coli E. coli
Thought to be involved in DNA repair and/or mutagenesis. Its processivity is enhanced by the beta sliding clamp (dnaN) and clamp loader.
TMPJ-01386 STUB1 Protein, Human, Recombinant

Carboxy Terminus of Hsp70-Interacting Protein,STIP1 Homology...

Human E. coli
E3 Ubiquitin-Protein Ligase CHIP is a cytoplasmic protein. CHIP is highly expressed in skeletal muscle, heart, pancreas, brain and placenta. CHIP interacts with the molecular chaperones Hsc70-Hsp70 and Hsp90 through its TPR domain; lead to in client substrate ubiquitylation and degradation by the proteasome. CHIP targets misfolded chaperone substrates towards proteasomal degradation. CHIP mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation....

重组蛋白

DNA PolymeraseBeta Protein, Human, Recombinant (His)
Cat.No: TMPJ-00792
Species: Human
Expression System: E. coli
DNA polymerase II Protein, E. coli, Recombinant (His & Myc)
Cat.No: TMPH-00613
Species: E. coli
Expression System: E. coli
STUB1 Protein, Human, Recombinant
Cat.No: TMPJ-01386
Species: Human
Expression System: E. coli
TargetMol Loading
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