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Cat. No. Product Name Target Signaling Pathways
T16557 PNU-159682

Topoisomerase DNA Damage/DNA Repair
PNU-159682 是蒽环类新霉素的代谢产物,是一种 DNA 拓扑异构酶 II 抑制剂,具有出色的细胞毒性。
T13658 DMEA-PNU-159682

Others Others
DMEA-PNU-159682 (molecule D12) is an ADC cytotoxin molecule, including neomycin (MMDX) metabolites from liver microsomes and effective ADC cytotoxin PNU-159682.
T19523 PNU-159682 carboxylic acid

Others Others
PNU-159682 carboxylic acid is a potent ADCs cytotoxin,PNU-159682 carboxylic acid has protein fold and diverse functions.
T18246 Mal-C2-Gly3-EDA-PNU-159682

Others Others
Mal-C2-Gly3-EDA-PNU-159682, a drug-linker conjugate for antibody-drug conjugates (ADC), combines the cleavable ADC linker Mal-C2-Gly3-EDA with the potent ADC cytotoxin PNU-159682.
T18302 Mal-Phe-C4-VC-PAB-DMEA-PNU-159682

Others Others
Mal-Phe-C4-VC-PAB-DMEA-PNU-159682 is a drug-linker conjugate utilized in antibody-drug conjugate (ADC) therapy. It comprises the ADC linker Mal-Phe-C4-VC-PAB and the potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 encompasses metabolites of nemorubicin (MMDX) derived from liver microsomes, as well as the ADC cytotoxin PNU-159682[1].
T17802 DBCO-PEG4-VC-PAB-DMEA-PNU-159682

Others Others
DBCO-PEG4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate for antibody-drug conjugates (ADC), comprises the ADC linker DBCO-PEG4-VC-PAB and the potent ADC cytotoxin DMEA-PNU-159682. The cytotoxin includes metabolites of nemorubicin (MMDX) from liver microsomes and the ADC cytotoxin PNU-159682[1].
T18292 Mal-PEG4-VC-PAB-DMEA-PNU-159682

Others Others
Mal-PEG4-VC-PAB-DMEA-PNU-159682 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) therapy. It combines the ADC linker, Mal-PEG4-VC-PAB, with the potent ADC cytotoxin, DMEA-PNU-159682. The cytotoxin, DMEA-PNU-159682, is derived from metabolites of nemorubicin (MMDX) found in liver microsomes, as well as the ADC cytotoxin PNU-159682[1].
T39373 PNU-EDA-Gly5

PNU-EDA-Gly5

PNU-EDA-Gly5 is a DNA topoisomerase I inhibitor-based oligo-glycine linker-payload used for the synthesis of antibody-drug conjugates (ADCs). It consists of the DNA topoisomerase I inhibitor PNU-159682 and the linker EDA-Gly5.

化合物

PNU-159682
Cat.No: T16557
Synonym:
Target: Topoisomerase
DMEA-PNU-159682
Cat.No: T13658
Synonym:
Target: Others
PNU-159682 carboxylic acid
Cat.No: T19523
Synonym:
Target: Others
Mal-C2-Gly3-EDA-PNU-159682
Cat.No: T18246
Synonym:
Target: Others
Mal-Phe-C4-VC-PAB-DMEA-PNU-159682
Cat.No: T18302
Synonym:
Target: Others
DBCO-PEG4-VC-PAB-DMEA-PNU-159682
Cat.No: T17802
Synonym:
Target: Others
Mal-PEG4-VC-PAB-DMEA-PNU-159682
Cat.No: T18292
Synonym:
Target: Others
PNU-EDA-Gly5
Cat.No: T39373
Synonym: PNU-EDA-Gly5
Target:
TargetMol Loading
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