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Cat. No. | Product Name | Target | Signaling Pathways |
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T68183 |
PPMC
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The alpha-adrenoceptors blocking effect of (N-piperidinomethyl)-2-chromanne was studied in vivo and in vitro in the rat. In the pithed rat, (N-piperidinomethyl)-2-chromanne (1 mg/kg i.v.) antagonized the pressor effects induced by alpha agonists. (N-piperidinomethyl)-2-chromanne competitively antagonized the pressor effects of M7 (alpha 2-agonist) and cirazoline (alpha 1-agonist). (N-piperidinomethyl)-2-chromanne antagonized the inhibitory effects of clonidine on presynaptic alpha 2-receptors in... |
Cat. No. | Product Name | Target | Signaling Pathways |
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T14008 |
2,2,5,7,8-Pentamethyl-6-Chromanol
PMC |
Androgen Receptor | Endocrinology/Hormones |
2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) 是维生素 E (α-tocopherol) 的抗氧化部分,能够有效的调节雄激素受体 (androgen receptor) 信号,及抗前列腺癌细胞系的抗癌活性。 |