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Targets Recommended: Neurotensin Receptor

5

抑制剂 & 化合物

2

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T9044 SORT-PGRN interaction inhibitor 1

Neurotensin Receptor GPCR/G Protein
SORT-PGRN interaction inhibitor 1 是一种 sortilin-progranulin 相互作用抑制剂,IC50为 2 μM。
T81126 SORT-PGRN interaction inhibitor 2

SORT-PGRN interaction inhibitor 2为一种SORT-PGRN抑制剂,能降低哺乳动物细胞中SORT1蛋白水平并提升PGRN在细胞外的分泌,适于神经系统疾病研究之用。
T79106 SORT-PGRN interaction inhibitor 3

Neurotensin Receptor GPCR/G Protein
SORT-PGRN interaction inhibitor 3(Compound 13),一种IC50为0.17 μM的SORT-PGRN相互作用抑制剂,适用于神经退行性疾病研究。
T77053 Latozinemab

GSK-4527223,AL-001

Neurotensin Receptor GPCR/G Protein
Latozinemab (AL001) 是一种具有有效性和选择性的重组人源化针对 Sortilin 的单克隆抗体。Latozinemab 对 Sortilin具有很高的亲和力,可中断颗粒蛋白前体 (PGRN) 和 Sortilin 受体之间的相互作用。Latozinemab 可用于研究痴呆和阿尔兹海默症。
T79105 BVFP

Neurotensin Receptor GPCR/G Protein
BVFP结合PGRN588-593肽,其解离常数(Kd)为20 μM。此外,BVFP能够阻断PGRN与SORT1的结合,并抑制SORT1介导的rPGRN内吞。

化合物

SORT-PGRN interaction inhibitor 1
Cat.No: T9044
Synonym:
Target: Neurotensin Receptor
SORT-PGRN interaction inhibitor 2
Cat.No: T81126
Synonym:
Target:
SORT-PGRN interaction inhibitor 3
Cat.No: T79106
Synonym:
Target: Neurotensin Receptor
Latozinemab
Cat.No: T77053
Synonym: GSK-4527223,AL-001
Target: Neurotensin Receptor
BVFP
Cat.No: T79105
Synonym:
Target: Neurotensin Receptor
Cat. No. Product Name Species Expression System
TMPY-00978 Progranulin Protein, Human, Recombinant (His)

PGRN,PCDGF,CLN11,Granulin,GP88,GEP,Granulin Precurs...

Human HEK293 Cells
Progranulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63.2 kDa and the accession number is P28799-1.
TMPY-01435 Progranulin Protein, Mouse, Recombinant (His)

Granulin Precursor,Pgrn,epithelin

Mouse HEK293 Cells
Progranulin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63 kDa and the accession number is P28798.

重组蛋白

Progranulin Protein, Human, Recombinant (His)
Cat.No: TMPY-00978
Species: Human
Expression System: HEK293 Cells
Progranulin Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01435
Species: Mouse
Expression System: HEK293 Cells
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