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Cat. No.	Product Name	Target	Signaling Pathways
T5382L	PF-06651600 malonate PF 06651600,PF-06651600,PF06651600
	PF-06651600 is a potent and selective JAK3 inhibitor.
T5382	Ritlecitinib PF-06651600	JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	Ritlecitinib (PF-06651600) 是一种口服有效的选择性JAK3抑制剂，IC50值为 33.1 nM。
T69821	AMP423
	AMP423 is a naphthyl derivative of 2-cyanoaziridine-1-carboxamide with structural similarity to the pro-oxidant anti-tumor agent imexon. AMP423 was active in SCID mice bearing 8226/S myeloma and SU-DHL-6 B-cell lymphoma tumors, with a median tumor growth delay (T-C) of 21 days (P = 0.0002) and 5 days (P = 0.004), respectively, and a median tumor growth inhibition (T/C) of 33.3% (P = 0.03) and 82% (P = 0.01), respectively. In non-tumor-bearing mice, AMP423 was not myelosuppressive.