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Search Results for " pdgfrb "

1

抑制剂 & 化合物

14

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T70424	EBI-907
	EBI-907 is a highly potent and orally efficacious B-RafV600E inhibitor. EBI-907 displays a low single-digit nanomolar activity (IC50 = 4.9 nM), which is >10-fold more potent than Vemurafenib (IC50 = 59 nM). EBI-907 also exhibits high potency in selectively inhibiting the proliferation of BRAF (V600E)-dependent cell lines (A375 and Colo205) and cellular Erk phosporylation, with superior activity to Vemurafenib. EBI-907, displaying potent activity against a number of important oncogenic kinases i...

化合物

Cat.No: T70424

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-05358	PDGFRB Protein, Human, Recombinant PENTT,platelet-derived growth factor receptor, beta polypept...	Human	HEK293 Cells
	PDGFRB Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 56.2 kDa and the accession number is P09619-1.
TMPY-03140	PDGFRB Protein, Rat, Recombinant (His) platelet-derived growth factor receptor, beta polypeptide,pl...	Rat	HEK293 Cells
	PDGFRB Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is Q05030.
TMPY-05497	PDGFRB Protein, Human, Recombinant (hFc) PDGFR,CD140B,PENTT,JTK12,KOGS,platelet-derived growth factor...	Human	HEK293 Cells
	PDGFRB Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.8 kDa and the accession number is P09619-1.
TMPY-03474	PDGFRB Protein, Rat, Recombinant (hFc) platelet-derived growth factor receptor, β polypeptide,plate...	Rat	HEK293 Cells
	PDGFRB Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.2 kDa and the accession number is Q05030.
TMPY-00385	PDGFRB Protein, Rhesus, Recombinant (hFc) platelet-derived growth factor receptor, β polypeptide,plate...	Rhesus	HEK293 Cells
	PDGFRB Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.3 kDa and the accession number is F7BTH1.
TMPY-03590	PDGFRB Protein, Rhesus, Recombinant (His) platelet-derived growth factor receptor, β polypeptide,plate...	Rhesus	HEK293 Cells
	PDGFRB Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is F7BTH1.
TMPY-01207	PDGFRB Protein, Human, Recombinant (His) CD140B,IMF1,KOGS,PDGFR,PDGFR-1,platelet-derived growth facto...	Human	HEK293 Cells
	PDGFRB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is P09619-1.
TMPY-04937	PDGFRB Protein, Human, Recombinant (His), Biotinylated platelet-derived growth factor receptor, beta polypeptide,CD...	Human	HEK293 Cells
	PDGFRB Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is P09619-1.
TMPK-01050	PDGF R beta/CD140b Protein, Canine, Recombinant (His) JTK12,PDGF R β,PDGFR-β,PDGFR,PDGFRB,PDGF R beta,PDG...	Canine	HEK293 Cells
	PDGF R beta/CD140b Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.25 kDa and the accession number is Q6QNF3.
TMPK-00422	PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated PDGFR-2,PDGF R β/CD140b,PDGFR1,CD140B,PDGFR,PDGF R β,JTK12,P...	Human	HEK293 Cells
	PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59 kDa and the accession number is P09619.
TMPK-00481	PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His) PDGF R beta,PDGFRB,PDGFR-2,PDGF-R-β,PDGF-R-beta,PDG...	Cynomolgus	HEK293 Cells
	Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β signalling, may be crucial for restoration of BBB integrity after cerebral ischemia and therefore represents a novel potential therapeutic target.
TMPK-00421	PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi) PDGFR1,CD140B,PDGFR-2,PDGF R β/CD140b,PDGF R beta,PDGFRB...	Human	HEK293 Cells
	PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59 kDa and the accession number is P09619.
TMPJ-00870	NCK1 Protein, Human, Recombinant (His) SH2/SH3 Adaptor Protein NCK-α,SH2/SH3 Adaptor Protein NCK-Al...	Human	E. coli
	Cytoplasmic Protein NCK1 (NCK1) is a cytoplasmic protein that contains one SH2 domain and three SH3 domains. NCK1 is a member of the adapter family, which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. NCK1 maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. NCK1 plays a role in the DNA damage response, but not in the detection of the damage by ATM/ATR. It is also involved in transducing...
TMPY-03439	UBASH3A Protein, Human, Recombinant (aa 354-623, His) TULA,STS-2,CLIP4,ubiquitin associated and SH3 domain contain...	Human	E. coli
	UBASH3A is a member of the T-cell ubiquitin ligand (TULA) family. This family consists of two members. Both of them can negatively regulate T-cell signaling. UBASH3A can facilitate growth factor withdrawal-induced apoptosis in T cells, which may occur via its interaction with AIF, an apoptosis-inducing factor. Alternative splicing of UBASH3A gene results in multiple transcript variants. It interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. UBASH3A pro...

重组蛋白

PDGFRB Protein, Human, Recombinant

Cat.No: TMPY-05358

Species: Human

Expression System: HEK293 Cells

PDGFRB Protein, Rat, Recombinant (His)

Cat.No: TMPY-03140

Species: Rat

Expression System: HEK293 Cells

PDGFRB Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05497

Species: Human

Expression System: HEK293 Cells

PDGFRB Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-03474

Species: Rat

Expression System: HEK293 Cells

PDGFRB Protein, Rhesus, Recombinant (hFc)

Cat.No: TMPY-00385

Species: Rhesus

Expression System: HEK293 Cells

PDGFRB Protein, Rhesus, Recombinant (His)

Cat.No: TMPY-03590

Species: Rhesus

Expression System: HEK293 Cells

PDGFRB Protein, Human, Recombinant (His)

Cat.No: TMPY-01207

Species: Human

Expression System: HEK293 Cells

PDGFRB Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-04937

Species: Human

Expression System: HEK293 Cells

PDGF R beta/CD140b Protein, Canine, Recombinant (His)

Cat.No: TMPK-01050

Species: Canine

Expression System: HEK293 Cells

PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00422

Species: Human

Expression System: HEK293 Cells

PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00481

Species: Cynomolgus

Expression System: HEK293 Cells

PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00421

Species: Human

Expression System: HEK293 Cells

NCK1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00870

Species: Human

Expression System: E. coli

UBASH3A Protein, Human, Recombinant (aa 354-623, His)

Cat.No: TMPY-03439

Species: Human

Expression System: E. coli

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