Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12377 |
PD-1-IN-17
|
PD-1/PD-L1 | Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation |
PD-1-IN-17 是程序性细胞死亡 1 (PD-1) 的抑制剂。 PD-1-IN-17 在 100 nM 时抑制 92% 的脾细胞增殖。 | |||
T12377L |
PD-1-IN-17 (TFA) (1673560-66-1 free base)
PD-1-IN-17 (TFA) |
Others | Others |
PD-1-IN-17 TFA is a inhibitor of programmed cell death-1 (PD-1) . | |||
T63256 | PD-1-IN-17 TFA | ||
PD-1-IN-17 TFA 是程序性细胞死亡-1 (PD-1) 的有效抑制剂,100 nM 的浓度能够抑制 92% 脾细胞增殖。 | |||
T62501 | PD-1/PD-L1-IN-17 | ||
PD-1/PD-L1-IN-17 (Compound P20) 是一种有效的 PD-1/PD-L1 抑制剂 (IC50: 26.8 nM)。PD-1/PD-L1-IN-17 是一种很有前途的先导化合物,能够用于 PD-1/PD-L1 相互作用抑制剂的开发。PD-1/PD-L1-IN-17 具有潜力进行癌症疾病的研究。 | |||
T61929 | PD-1/PD-L1-IN-14 | ||
PD-1/PD-L1-IN-14 (compound 17) 是PD-1/PD-L1相互作用的抑制剂(IC50= 27.8 nM)。通过抑制PD-1/PD-L1 相互作用,PD-1/PD-L1-IN-14促进二聚化,内吞作用并降解 PD-L1。 | |||
T10589L |
BPN-15606
|
Others | Others |
BPN-15606 is a highly potent, orally active γ-secretase modulator (GSM), attenuates the production of Aβ42 and Aβ40 by SHSY5Y neuroblastoma cells with IC50 values of 7 nM and 17nM, respectively. BPN-15606 has acceptable PK/PD properties, including bioavai |