Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T81544 |
PARP1-IN-16
|
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
PARP1-IN-16(化合物12a)是一款高效的PARP1抑制剂,其IC50为1.89 nM。该化合物能够促使细胞周期在S期停滞,并引发HCT-116细胞的凋亡。 | |||
T16334 |
NMS-P515
|
Others | Others |
NMS-P515 is an effective, orally active, and stereospecific PARP-1 inhibitor (Kd: 16 nM and an IC50: 27 nM (in Hela cells)). It has anti-tumor activity. |