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Cat. No. Product Name Target Signaling Pathways
TP1878L PACAP 1-38 acetate

PACAP GPCR/G Protein
PACAP 1-38 acetate 是一种垂体腺苷酸环化酶激活多肽 (PACAP) 类似物。它与 PACAP I 型受体 (IC50 = 4 nM) 和 PACAP II 型 VIP2 受体 (IC50 = 1 nM) 结合,但不与 PACAP II 型 VIP1 受体结合。
TP1878 PACAP (1-38), human, ovine, rat

Pituitary Adenylate Cyclase Activating Polypeptide 38,腺苷酸环化酶激活肽-38(抗原),PACAP 1-38

PACAP GPCR/G Protein
PACAP (1-38), human, ovine, rat (Pituitary Adenylate Cyclase Activating Polypeptide 38) 是含有 38 个氨基酸残基的神经肽。它能够结合 PACAP I 型受体(IC50:4 nM)、PACAP II 型受体 VIP1(IC50:2 nM)、PACAP II 型受体 VIP2(IC50:1 nM)。
TP1054 PACAP (1-38), human, ovine, rat TFA

Pituitary Adenylate Cyclase Activating Polypeptide 38 (TFA)

PACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM). PACAP 1-38 (10-9 M) increased substance P (SP), gastrin releasing peptide (GRP),
T81572 PACAP (1-38) free acid

PACAP (1-38) free acid 是一种具有多重生物功能的内源性神经肽,主要作用包括刺激胃窦运动、增进体液蛋白分泌、抑制胃泌素分泌,以及促进血管活性肠肽、胃泌素释放肽和P 物质的释放。此外,PACAP (1-38) free acid 通过与RACK1互作,可以增强N-甲基-D-天门冬氨酸受体的功能并促进脑源性神经营养因子的表达。
T81571 PACAP (1-38) free acid TFA

PACAP (1-38) free acid TFA,一种内源性神经肽,能有效促进胃窦运动,增强体液蛋白分泌,同时抑制胃泌素释放。此外,它刺激血管活性肠肽、胃泌素释放肽和P物质的释放,并通过RACK1增强N-甲基-D-天门冬氨酸受体功能及脑源性神经营养因子表达。
TP1070 PACAP (1-27), human, ovine, rat

PACAP 1-27

PACAP (1-27) (the N-terminal fragment of PACAP-38) is a novel neuropeptides originally isolated from bovine hypothalamus, also found in humans and rats.
TP1069 PACAP (1-27), human, ovine, rat TFA

PACAP 1-27 TFA

PACAP (1-27), human, ovine, rat TFA (PACAP 1-27 TFA) is an N-terminal fragment of pacap-38 and an effective PACAP receptor antagonist. The IC50s for rat PAC1, rat VPAC1 and human VPAC2 are 3nm, 2nm and 5nm respectively.
T36427 PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)

PACAP GPCR/G Protein
Pituitary adenylate cyclase-activating peptide (PACAP) (6-27) is a PACAP receptor antagonist with IC50 values of 1,500, 600, and 300 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors expressed in CHO cells. It binds to PACAP receptors on SH-SY5Y and SK-N-MC human neuroblastoma and T47D human breast cancer cells (IC50s = 24.5, 106, and 105 nM, respectively) and inhibits cAMP accumulation induced by PACAP (1-38) (Kis = 457, 102, and 283 nM, respectively, in SH-SY5Y, ...

化合物

PACAP 1-38 acetate
Cat.No: TP1878L
Synonym:
Target: PACAP
PACAP (1-38), human, ovine, rat
Cat.No: TP1878
Synonym: Pituitary Adenylate Cyclase Activating Polypeptide 38,腺苷酸环化酶激活肽-38(抗原),PACAP 1-38
Target: PACAP
PACAP (1-38), human, ovine, rat TFA
Cat.No: TP1054
Synonym: Pituitary Adenylate Cyclase Activating Polypeptide 38 (TFA)
Target:
PACAP (1-38) free acid
Cat.No: T81572
Synonym:
Target:
PACAP (1-38) free acid TFA
Cat.No: T81571
Synonym:
Target:
PACAP (1-27), human, ovine, rat
Cat.No: TP1070
Synonym: PACAP 1-27
Target:
PACAP (1-27), human, ovine, rat TFA
Cat.No: TP1069
Synonym: PACAP 1-27 TFA
Target:
PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)
Cat.No: T36427
Synonym:
Target: PACAP
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