Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP1070L |
PACAP (1-27), human, ovine, rat acetate
PACAP 1-27 acetate,PACAP (1-27), human, ovine, rat acetate(127317-03-7 free base) |
PACAP | GPCR/G Protein |
PACAP (1-27), human, ovine, rat acetate (PACAP 1-27 acetate)(127317-03-7 free base) 是一种新的神经肽,最初从牛下丘脑中分离出来,也存在于人和大鼠中。 | |||
TP1070 |
PACAP (1-27), human, ovine, rat
PACAP 1-27 |
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PACAP (1-27) (the N-terminal fragment of PACAP-38) is a novel neuropeptides originally isolated from bovine hypothalamus, also found in humans and rats. | |||
TP1069 |
PACAP (1-27), human, ovine, rat TFA
PACAP 1-27 TFA |
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PACAP (1-27), human, ovine, rat TFA (PACAP 1-27 TFA) is an N-terminal fragment of pacap-38 and an effective PACAP receptor antagonist. The IC50s for rat PAC1, rat VPAC1 and human VPAC2 are 3nm, 2nm and 5nm respectively. | |||
T83510 |
[Arg-15,20,21,Leu17]-PACAP-Gly-Lys-Arg-NH2
BM-PACAP |
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[Arg-15,-20,-21,Leu17]-PACAP-Gly-Lys-Arg-NH2 (BM-PACAP) 为合成PACAP 1-27 类似物,展现出明显的松弛效应。 | |||
T36427 |
PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)
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PACAP | GPCR/G Protein |
Pituitary adenylate cyclase-activating peptide (PACAP) (6-27) is a PACAP receptor antagonist with IC50 values of 1,500, 600, and 300 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors expressed in CHO cells. It binds to PACAP receptors on SH-SY5Y and SK-N-MC human neuroblastoma and T47D human breast cancer cells (IC50s = 24.5, 106, and 105 nM, respectively) and inhibits cAMP accumulation induced by PACAP (1-38) (Kis = 457, 102, and 283 nM, respectively, in SH-SY5Y, ... | |||
T80069 |
PACAP (6-27) (human, ovine, rat)
Pituitary adenylate cyclase-activating peptide (6-27) |
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PACAP (6-27) (human, ovine, rat) 是一种对PACAP受体具有拮抗作用的化合物,可以抑制犬肾上腺对外源性VIP的反应。此化合物在心血管疾病和神经系统疾病研究中展现出应用潜力。 |