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Cat. No. Product Name Target Signaling Pathways
T36427 PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)

PACAP GPCR/G Protein
Pituitary adenylate cyclase-activating peptide (PACAP) (6-27) is a PACAP receptor antagonist with IC50 values of 1,500, 600, and 300 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors expressed in CHO cells. It binds to PACAP receptors on SH-SY5Y and SK-N-MC human neuroblastoma and T47D human breast cancer cells (IC50s = 24.5, 106, and 105 nM, respectively) and inhibits cAMP accumulation induced by PACAP (1-38) (Kis = 457, 102, and 283 nM, respectively, in SH-SY5Y, ...
T80069 PACAP (6-27) (human, ovine, rat)

Pituitary adenylate cyclase-activating peptide (6-27)

PACAP (6-27) (human, ovine, rat) 是一种对PACAP受体具有拮抗作用的化合物,可以抑制犬肾上腺对外源性VIP的反应。此化合物在心血管疾病和神经系统疾病研究中展现出应用潜力。
TP1722 PACAP (6-38), human, ovine, rat

PACAP (6-38), human, ovine, rat is a potent antagonist of PACAP 38. PACAP (6-38) is much more potent and selective than PACAP (6-27) in the inhibition of PACAP-27-stimulated pituitary adenylate cyclase.

化合物

PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)
Cat.No: T36427
Synonym:
Target: PACAP
PACAP (6-27) (human, ovine, rat)
Cat.No: T80069
Synonym: Pituitary adenylate cyclase-activating peptide (6-27)
Target:
PACAP (6-38), human, ovine, rat
Cat.No: TP1722
Synonym:
Target:
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