Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16422 |
P110δ-IN-1
PWT-143 |
PI3K | PI3K/Akt/mTOR signaling |
P110δ-IN-1 (PWT-143) 是一种有效的、选择性的P110δ抑制剂,其 IC50=8.4 nM。 | |||
T78568 |
PI3Kδ-IN-15
|
PI3K | PI3K/Akt/mTOR signaling |
PI3Kδ-IN-15(compound 6b)为一选择性PI3Kδ抑制剂,p110δ的IC50为0.5 nM,其对PI3Kδ的抑制效力高于PI3Kγ、PI3Kβ及PI3Kα30倍。 | |||
T14191 |
Alpelisib hydrochloride
BYL-719 hydrochloride |
Others | Others |
Alpelisib hydrochloride (BYL-719 hydrochloride) shows antineoplastic activity[1][2]. Alpelisib hydrochloride (BYL-719 hydrochloride) is a potent, orally active, and selective PI3Kα inhibitor with IC50s of 5 nM, 250 nM, 290 nM and 1200 nM for p110α, p110γ, |