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Cat. No. Product Name Target Signaling Pathways
T16422 P11-IN-1

PWT-143

PI3K PI3K/Akt/mTOR signaling
P11-IN-1 (PWT-143) 是一种有效的、选择性的P11抑制剂,其 IC50=8.4 nM。
T78568 PI3Kδ-IN-15

PI3K PI3K/Akt/mTOR signaling
PI3Kδ-IN-15(compound 6b)为一选择性PI3Kδ抑制剂,p11的IC50为0.5 nM,其对PI3Kδ的抑制效力高于PI3Kγ、PI3Kβ及PI3Kα30倍。
T14191 Alpelisib hydrochloride

BYL-719 hydrochloride

Others Others
Alpelisib hydrochloride (BYL-719 hydrochloride) shows antineoplastic activity[1][2]. Alpelisib hydrochloride (BYL-719 hydrochloride) is a potent, orally active, and selective PI3Kα inhibitor with IC50s of 5 nM, 250 nM, 290 nM and 1200 nM for p110α, p110γ,

化合物

P11-IN-1
Cat.No: T16422
Synonym: PWT-143
Target: PI3K
PI3Kδ-IN-15
Cat.No: T78568
Synonym:
Target: PI3K
Alpelisib hydrochloride
Cat.No: T14191
Synonym: BYL-719 hydrochloride
Target: Others
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