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Cat. No. | Product Name | Target | Signaling Pathways |
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T62820 | OPN expression inhibitor 1 | ||
OPN expression inhibitor 1 (Compound 11),一种针对骨钙素 (osteopontin (OPN)) 表达的抑制剂,适用于乳腺癌研究。 | |||
TP1582 |
Gly-Arg-Gly-Asp-Ser (TFA)(96426-21-0,free)
Gly-Arg-Gly-Asp-Ser (TFA) |
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Gly-Arg-Gly-Asp-Ser (GRGDS) is a cell binding protein domain derived from the cell-binding region of fibronectin. Osteopontin uses this motif for cell adhesion. | |||
T75761 |
Gly-Arg-Gly-Asp-Ser TFA
GRGDS TFA |
||
Gly-Arg-Gly-Asp-Ser (TFA) 是一种与糖蛋白和骨桥蛋白在细胞结合域中起作用的五肽。该化合物能够与整合素整联蛋白受体αvβ3和αvβ5结合,其IC50值分别约为5 μM和6.5 μM。 | |||
T26456 |
A 83586C
A83586C,A-83586C |
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A-83586C is a depsipeptide antibiotic from Streptomyces karnatakensis with potent against Gram-positive activity in vitro. A-83586C acts as a highly potent inhibitor of beta-catenin/TCF4 signaling within cancer cells, while simultaneously downregulating o |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T26358 |
(-)-Agelastatin A
|
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(-)-Agelastatin A inhibits osteopontin-mediated adhesion, invasion, and colony formation. |
Cat. No. | Product Name | Species | Expression System |
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TMPK-00807 |
Osteopontin Protein, Mouse, Recombinant (His)
ETA-1,SPP1,OPN,Bone sialoprotein 1,BNSP,SPP-1,Osteoponti... |
Mouse | HEK293 Cells |
Secreted phosphoprotein 1 (SPP1) expression in TAMs isolated from lung adenocarcinoma tissues and PMA-treated THP-1 cells were measured. Macrophage polarization was identified by flow cytometric analysis. Cell migration and apoptosis were assessed by Transwell migration assays and flow cytometric analysis, respectively. SPP1 is highly expressed in tumor tissues and TAMs isolated from patients with an advanced TNM stage, and also in PMA-treated THP-1 cells. | |||
TMPY-01288 |
Osteopontin Protein, Human, Recombinant (His)
OPN,BSPI,BNSP,ETA-1,secreted phosphoprotein 1 |
Human | HEK293 Cells |
Osteopontin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35 kDa and the accession number is A0A024RDE2. | |||
TMPK-00538 |
Osteopontin Protein, Cynomolgus, Recombinant (His)
BSP-1,BNSP,SPP1,Nephropontin,OPN,Bone sialoprotein 1,ETA-1,<... |
Cynomolgus | HEK293 Cells |
Osteopontin Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 33.16 kDa and the accession number is A0A2K5WL90. | |||
TMPK-00676 |
Osteopontin Protein, Human, Recombinant (aa 17-300, His)
BSP-1,Nephropontin,BNSP,ETA-1,OPN,Bone sialoprotein 1,BSPI,U... |
Human | HEK293 Cells |
Osteopontin Protein, Human, Recombinant (aa 17-300, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 34.8 kDa and the accession number is A0A024RDE6. | |||
TMPY-06988 |
Osteopontin Protein, Human, Recombinant (aa 17-166, His)
BNSP,ETA-1,OPN,BSPI |
Human | HEK293 Cells |
Osteopontin Protein, Human, Recombinant (aa 17-166, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.64 kDa. and the accession number is P10451. | |||
TMPY-05716 |
Integrin alpha V beta 3 Protein, Human, Recombinant (His)
Integrin α V β 3,Integrin alpha V β3 |
Human | HEK293 Cells |
Integrin alpha-V & beta-3 (ITGAV/ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. | |||
TMPK-01028 |
BSPII Protein, Mouse, Recombinant (His)
IBSP,SP II,BSP,BSP II,BNSP,BSP-II,BSP 2,SPII,SP-II |
Mouse | HEK293 Cells |
Osteopontin (OPN), bone sialoprotein (BSPII), and osteonectin (ON) belong to a family of glycoproteins, which have been linked to cancer metastasis and progression. Here, we report on the selection of antisense oligonucleotides (ASOs), which are effective in reducing their protein levels. |