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Targets Recommended: Acyltransferase

8

抑制剂 & 化合物

2

天然产物

2

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T10035 10,12-Tricosadiynoic acid

TDA,TCDA

Acyltransferase Metabolism
10,12-Tricosadiynoic acid 是一种口服有效的酰基辅酶 A 氧化酶-1 (ACOX1) 抑制剂,具有高特异性,选择性,高亲和力的特点。10,12-Tricosadiynoic acid 可改善线粒体脂质和 ROS 代谢,在高脂饮食或肥胖引起的代谢性疾病中有研究的价值。
T16716 Rabacfosadine

VDC-1101,GS-9219

Others Others
Rabacfosadine (GS-9219) 是无环核苷酸膦酸 PMEG 的新型前药,具有抗肿瘤活性,可用于研究淋巴瘤。
T37922 7(Z),11(Z)-Pentacosadiene

Unsaturated, long-chain hydrocarbons are found on the cuticles of insects and can act as pheromones. In mature Drosophila melanogaster, certain cuticular hydrocarbons are sexually dimorphic: males synthesize 23- and 25-C monoenes and females produce 27- and 29-C dienes. Each of these lipids plays specific roles in regulating male sexual behavior, with dienes stimulating courtship. 7(Z),11(Z)-Pentacosadiene is a 25-C hydrocarbon that is found in low abundance on cuticles of mature Drosophila fema...
T37921 7(Z),11(Z)-Nonacosadiene

Unsaturated cuticular hydrocarbons serve as pheromones in insects. In D. melanogaster, these hydrocarbons are sexually dimorphic in both their occurrence and their effects. 7(Z),11(Z)-Nonacosadiene is a cuticular pheromone in female fruit flies that stimulates male courtship behavior. The biosynthesis of this C29 diene appears to be mediated by an elongase with female-based expression.
T38341 11(Z),14(Z)-Eicosadienoic Acid methyl ester

11(Z),14(Z)-Eicosadienoic acid methyl ester is a more lipid soluble form of the ω-6 C20-2 fatty acid 11(Z),14(Z)-eicosadienoic acid , a naturally occurring PUFA. 11(Z),14(Z)-Eicosadienoic acid competitively inhibits inosine 5'-monophosphate dehydrogenase (Ki = 3.1 μM) and inhibits the binding of LTB4 to its receptor on neutrophils (Ki = 3.0 μM). Also, serum levels of eicosadienoic acids negatively correlate with degree of sleep disturbance. Eicosadienoic acids are converted by desaturases, in vi...
T37920 7(Z),11(Z)-Heptacosadiene

The mating and social behaviors of insects are largely orchestrated by a suite of volatile cuticular hydrocarbon pheromones. 7(Z),11(Z)-Heptacosadiene is the predominant female-specific courtship pheromone of the fruit fly D. melanogaster. At amounts above 100 ng, 7(Z),11(Z)-heptacosadiene elicits wing vibrations in male D. melanogaster flies in a dose-dependent manner.
T24702 Rabacfosadine succinate

VDC-1101 succinate,GS-9219 succinate,VDC 1101 succinate VDC1101 succinate,GS-9219-01

Rabacfosadine succinate is the acyclic nucleoside phosphonate PMEG double prodrug.
T19750 Spinosad Factor D

Spinosad Factor D is a naturally derived fermentation product. It is used as a pesticide against many different insects.

化合物

10,12-Tricosadiynoic acid
Cat.No: T10035
Synonym: TDA,TCDA
Target: Acyltransferase
Rabacfosadine
Cat.No: T16716
Synonym: VDC-1101,GS-9219
Target: Others
7(Z),11(Z)-Pentacosadiene
Cat.No: T37922
Synonym:
Target:
7(Z),11(Z)-Nonacosadiene
Cat.No: T37921
Synonym:
Target:
11(Z),14(Z)-Eicosadienoic Acid methyl ester
Cat.No: T38341
Synonym:
Target:
7(Z),11(Z)-Heptacosadiene
Cat.No: T37920
Synonym:
Target:
Rabacfosadine succinate
Cat.No: T24702
Synonym: VDC-1101 succinate,GS-9219 succinate,VDC 1101 succinate VDC1101 succinate,GS-9219-01
Target:
Spinosad Factor D
Cat.No: T19750
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T7647 Eicosadienoic acid

二十碳二烯酸,11,14-二十碳二烯酸C20:2

Endogenous Metabolite Metabolism
Eicosadienoic acid 是天然存在的 n-6 多不饱和脂肪酸,主要再动物组织中获得。
T9076 Spinosad

Others Others
Spinosad 是在土壤细菌 S. spinosa 中发现的一种杀虫剂,是大环内酯多杀菌素 A 和多杀菌素 D 的混合物,可作为昆虫烟碱乙酰胆碱酯酶受体 (nAChRs) 的激动剂。它具有优良的环境和哺乳动物毒理学特征,以及杀灭幼虫的活性。

天然产物

Eicosadienoic acid
Cat.No: T7647
Synonym: 二十碳二烯酸,11,14-二十碳二烯酸C20:2
Target: Endogenous Metabolite
Spinosad
Cat.No: T9076
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPY-04487 Osteomodulin Protein, Human, Recombinant (His)

SLRR2C,osteomodulin,OSAD

Human HEK293 Cells
Osteomodulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.6 kDa and the accession number is Q99983.
TMPY-01472 Osteomodulin Protein, Mouse, Recombinant (His)

SLRR2C,osteomodulin,OSAD

Mouse HEK293 Cells
Osteomodulin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.8 kDa and the accession number is O35103.

重组蛋白

Osteomodulin Protein, Human, Recombinant (His)
Cat.No: TMPY-04487
Species: Human
Expression System: HEK293 Cells
Osteomodulin Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01472
Species: Mouse
Expression System: HEK293 Cells
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