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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7384 |
Ocifisertib(CFI-400945 free base)
|
PLK | Cell Cycle/Checkpoint |
CFI-400945 是一种有效的、选择性的、具有口服活性的 polo 样激酶 4(PLK4;Ki 值为 0.26 nM)的抑制剂。 | |||
T22645 | CFI-400945 | Others | Others |
CFI-400945 is an orally active, potent, and selective inhibitor of polo-like kinase 4. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-01466 |
Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)
OPG,Tumor Necrosis Factor Receptor Superfamily Member 11B, |
Human | HEK293 Cells |
TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits nuclear kappa B (NF-κB) which is a central and rapid acting transcription factor for immune-related genes, and a key regulator of inflammation, innate immunity, and cell survival and differentiation. TNFRSF11B levels are influenced by voltage-dependent calcium channelsCav1.2. TNF... | |||
TMPY-04509 |
Osteoprotegerin Protein, Mouse, Recombinant (hFc)
tumor necrosis factor receptor superfamily member 11b,Opg,TR... |
Mouse | HEK293 Cells |
Osteoprotegerin Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 70.2 kDa and the accession number is O08712. | |||
TMPJ-00253 |
OPG Protein, Mouse, Recombinant (His)
Opg,Ocif,Tnfrsf11b,Osteoclastogenesis inhibitory fa... |
Mouse | HEK293 Cells |
Osteoprotegerin (OPG, Tnfrsf11b) is a secreted protein that regulates bone density. OPG is widely expressed and constitutively released as a homodimer by mesenchymal stem cells, fibroblasts and endothelial cells. Regulation of its expression by estrogen, parathyroid hormone and cytokines is complex and changes with age. OPG acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. TRAIL decreases the release of OPG from cells that express it, while OPG ... | |||
TMPY-01724 |
Osteoprotegerin Protein, Human, Recombinant (His)
OCIF,OPG,MGC29565,TR1,PDB5,tumor necrosis factor re... |
Human | HEK293 Cells |
Osteoprotegerin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.3 kDa and the accession number is O00300. | |||
TMPY-05262 |
Osteoprotegerin Protein, Human, Recombinant (hFc)
MGC29565,OPG,PDB5,tumor necrosis factor receptor superfamily... |
Human | Baculovirus Insect Cells |
Osteoprotegerin Protein, Human, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 70.3 kDa and the accession number is O00300. |