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Search Results for " ocif "
Targets Recommended: PLK

2

抑制剂 & 化合物

5

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T7384 Ocifisertib(CFI-400945 free base)

PLK Cell Cycle/Checkpoint
CFI-400945 是一种有效的、选择性的、具有口服活性的 polo 样激酶 4(PLK4;Ki 值为 0.26 nM)的抑制剂。
T22645 CFI-400945

Others Others
CFI-400945 is an orally active, potent, and selective inhibitor of polo-like kinase 4.

化合物

Ocifisertib(CFI-400945 free base)
Cat.No: T7384
Synonym:
Target: PLK
CFI-400945
Cat.No: T22645
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPJ-01466 Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)

OPG,Tumor Necrosis Factor Receptor Superfamily Member 11B,

Human HEK293 Cells
TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits nuclear kappa B (NF-κB) which is a central and rapid acting transcription factor for immune-related genes, and a key regulator of inflammation, innate immunity, and cell survival and differentiation. TNFRSF11B levels are influenced by voltage-dependent calcium channelsCav1.2. TNF...
TMPY-04509 Osteoprotegerin Protein, Mouse, Recombinant (hFc)

tumor necrosis factor receptor superfamily member 11b,Opg,TR...

Mouse HEK293 Cells
Osteoprotegerin Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 70.2 kDa and the accession number is O08712.
TMPJ-00253 OPG Protein, Mouse, Recombinant (His)

Opg,Ocif,Tnfrsf11b,Osteoclastogenesis inhibitory fa...

Mouse HEK293 Cells
Osteoprotegerin (OPG, Tnfrsf11b) is a secreted protein that regulates bone density. OPG is widely expressed and constitutively released as a homodimer by mesenchymal stem cells, fibroblasts and endothelial cells. Regulation of its expression by estrogen, parathyroid hormone and cytokines is complex and changes with age. OPG acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. TRAIL decreases the release of OPG from cells that express it, while OPG ...
TMPY-01724 Osteoprotegerin Protein, Human, Recombinant (His)

OCIF,OPG,MGC29565,TR1,PDB5,tumor necrosis factor re...

Human HEK293 Cells
Osteoprotegerin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.3 kDa and the accession number is O00300.
TMPY-05262 Osteoprotegerin Protein, Human, Recombinant (hFc)

MGC29565,OPG,PDB5,tumor necrosis factor receptor superfamily...

Human Baculovirus Insect Cells
Osteoprotegerin Protein, Human, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 70.3 kDa and the accession number is O00300.

重组蛋白

Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)
Cat.No: TMPJ-01466
Species: Human
Expression System: HEK293 Cells
Osteoprotegerin Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-04509
Species: Mouse
Expression System: HEK293 Cells
OPG Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00253
Species: Mouse
Expression System: HEK293 Cells
Osteoprotegerin Protein, Human, Recombinant (His)
Cat.No: TMPY-01724
Species: Human
Expression System: HEK293 Cells
Osteoprotegerin Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05262
Species: Human
Expression System: Baculovirus Insect Cells
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