Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T23102 |
OBAA
|
Others | Others |
OBAA 是一种有效的磷脂酶 A2 (PLA2) 抑制剂(IC50= 70 nM),并且在布氏锥虫中阻断 Melittin 诱导的 Ca2+流入(IC50= 0.4 μM)。 | |||
T70943 |
AM-9635
|
||
AM-9635 is a potent and selective PI3Kδ inhibitor. AM-9635 showes good cellular potency (in vitro pAKT IC50 = 4.2 nM ). AM-96352 inhibits KLH-specific IgG and IgM in a dosedependent manner AM-9635 is well tolerated at all doses and exhibits significantly reduced IgG and IgM specific antibodies . PI3Kα and PI3Kβ are ubiquitously expressed and play a role in cell growth, division, and survival. |