Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T35904 |
O-11
|
||
O-11 is an analog of the fully saturated, 14-carbon fatty acid myristic acid, in which the methylene group at position 11 is replaced with oxygen. It is highly effective and selective at killingTrypanosoma brucei, the protozoan parasite responsible for African sleeping sickness, exhibiting an LD50of less than 1 μM in a cell culture assay.1,2The toxic effects of O-11 appear to be caused by its ability to inhibit the incorporation of a single myristate into the GPI anchor of the variant surface gl... | |||
T4436 |
RO1138452
CAY10441 |
Others; Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation; Others |
RO1138452 (CAY10441) 是一种选择性和可口服的前列环素受体拮抗剂,pKi 为8.3。它拮抗卡前列环素诱导的人神经母细胞瘤腺苷酸环化酶的激活,以剂量依赖性方式阻断环 AMP 积累,具有镇痛活性。 | |||
T34367 |
RO116-4875/608
RO 116-4875/608 |
||
RO116-4875/608 is bioactive chemical. | |||
T34368 |
RO116-9132/238
RO-116-9132/238,RO 116-9132/238 |
||
RO116-9132/238 is a bioactive chemical. | |||
T76755 | Panobacumab | ||
Panobacumab (KBPA101) 是一种完全人 IgM/κ 单克隆抗体,由人类 B 淋巴细胞产生,对血清型 O11P. aeruginosa 的 LPS O 多糖具有抗性。 |