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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T72002 Carbazomycin C

Carbazomycin C is a bacterial metabolite that has been found in Streptomyces and has diverse biological activities. It is active against S. aureus, B. anthracis, B. subtilis, and M. flavus, the fungi T. asteroides and T. mentagrophytes, and P. falciparum. It is also active against a panel of five plant pathogenic fungi. Carbazomycin C is cytotoxic to MCF-7, KB, and NCI H187 cells. It also inhibits 5-lipoxygenase (5-LO) activity in RBL-1 cell extracts.
T25798 Methyl Streptonigrin

NSC 45384,NSC45384,NSC-45384

Methyl Streptonigrin is an ABCG2 transporter function inhibitor.
T71483 Streptonigrin (racemate)

Streptonigrin is an aminoquinone antitumor and antibacterial antibiotic produced by Streptomyces flocculus. Streptonigrin inhibits β-Catenin/Tcf signaling and shows cytotoxicity in β-catenin-activated cells. Streptonigrin induces delayed chromosomal instability involving interstitial telomeric sequences in Chinese hamster ovary cells. Note: Streptonigrin from natural resource is (-)-rotation, has CAS#3930-19-6 and is a R-isomer.
T35607 10'-Desmethoxystreptonigrin

10'-Desmethoxystreptonigrin is an antibiotic originally isolated from Streptomyces and a derivative of the antibiotic streptonigrin. It is active against a variety of bacteria, including S. aureus, S. faecalis, E. coli, K. pneumoniae, and P. vulgaris (MICs = 0.4, 1.6, 3.1, 3.1 and 0.4 μg/ml, respectively). 10'-Desmethoxystreptonigrin is cytotoxic to HCT116 colon and A2780 ovarian cancer cells (IC50s = 0.004 and 0.001 μg/ml, respectively), as well as HCT116 cells resistant to etoposide and tenipo...
T130849 Aspernigrin A

Aspernigrin A 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T130849。

化合物

Carbazomycin C
Cat.No: T72002
Synonym:
Target:
Methyl Streptonigrin
Cat.No: T25798
Synonym: NSC 45384,NSC45384,NSC-45384
Target:
Streptonigrin (racemate)
Cat.No: T71483
Synonym:
Target:
10'-Desmethoxystreptonigrin
Cat.No: T35607
Synonym:
Target:
Aspernigrin A
Cat.No: T130849
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T2S0712 Sinigrin

黑芥子苷,Allylglucosinolate,2-Propenylglucosinolate

Others Others
Sinigrin (2-Propenylglucosinolate) 是十字花科植物中主要的硫代葡萄糖苷,具有抗脂肪生成作用。它在芥子油苷的分离和鉴定程序中用作参考材料。
T2S2104 Sinigrin hydrate

黑芥子苷,Sinigrin monohydrate,芥子甙单水合物,Allylglucosinolate monohydrate

Antibacterial Microbiology/Virology
Sinigrin hydrate (Allylglucosinolate monohydrate) 是一种天然脂肪族芥子油苷,存在于十字花科植物中。它具有消炎、抗癌、抗真菌、抗菌、抗氧化作用。
T36513 Pyranonigrin A

Pyranonigrin A is a fungal metabolite originally isolated from Aspergillus that has antioxidant activity. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH;) free radicals in a cell-free assay (IC50 = 132.9 μM). Pyranonigrin A (10 μM) suppresses TNF-α-induced expression of vascular cell adhesion molecule 1 (VCAM-1) in human umbilical vein endothelial cells (HUVECs).
T34506 Sambunigrin

(S)-Prunasin,L-Prunasin,(2S)-Sambunigrin

Sambunigrin is a cyanogenic glycoside.
T16946 Streptonigrin

Bruneomycin

Others Others
Streptonigrin is a natural product produced by Streptomyces flocculus, has both anti-tumor and anti-bacterial activity. Streptonigrin acts as a pan-PAD inhibitor (IC50s: 48.3±34.2 µM, 26.1±0.3 µM, 0.43±0.03 µM, and 2.5±0.4 µM for PAD1, PAD2, PAD3, and PAD

天然产物

Sinigrin
Cat.No: T2S0712
Synonym: 黑芥子苷,Allylglucosinolate,2-Propenylglucosinolate
Target: Others
Sinigrin hydrate
Cat.No: T2S2104
Synonym: 黑芥子苷,Sinigrin monohydrate,芥子甙单水合物,Allylglucosinolate monohydrate
Target: Antibacterial
Pyranonigrin A
Cat.No: T36513
Synonym:
Target:
Sambunigrin
Cat.No: T34506
Synonym: (S)-Prunasin,L-Prunasin,(2S)-Sambunigrin
Target:
Streptonigrin
Cat.No: T16946
Synonym: Bruneomycin
Target: Others
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