Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00293 |
Nectin-2 Protein, Human, Recombinant (His & Avi)
PRR2,CD112,Nectin2,MPH,P... |
Human | HEK293 Cells |
Nectin-2 is an adhesion molecule that has been reported to play a role in tumor growth, metastasis and tumor angiogenesis. Nectin-2 expression in ovarian cancer may support tumor cell adhesion, leading to growth and lymph node metastasis. Effect of VEGF on Nectin-2 expression as well as permeability was investigated in HUVEC. | |||
TMPJ-00323 |
Nectin-2 Protein, Mouse, Recombinant (hFc)
Herpes Virus Entry Mediator B,PVRL2,Poliovirus Rece... |
Mouse | HEK293 Cells |
CD112 is a type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. It comprises one Ig-like V-type domain and two Ig-like C2-type domains in the extracellular region. The V domain is believed to mediate nectin binding to its ligands. Nectin2 is known to bind the pseudorabies virus, and herpes simplex virus2 (HSV2), involving in cell to cell spreading of these viruses. It does not bind poliovirus. As a homophilic adhesion molecule, CD112 is found concentrated in adherens ju... |