Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3218 |
Napabucasin
BBI608 |
STAT | JAK/STAT signaling; Stem Cells |
Napabucasin (BBI608) 是一种口服的 Stat3 和 Y 干细胞活性抑制剂。 | |||
T36514 |
QD-394
|
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QD-394 is an inducer of reactive oxygen species (ROS) production.1It induces lipid peroxidation, increases in intracellular accumulation of reactive oxygen species (ROS), and decreases in the reduced glutathione (GSH) to oxidized GSH (GSSG) ratio in MIA PaCa-2 pancreatic cancer cells when used at concentrations ranging from 0.5 to 10 μM. QD-394 is cytotoxic to MIA PaCa-2, PANC-1, and BxPC-3 cancer cells (IC50s = 0.64, 0.34, and 0.9 μM, respectively). QD-394 acts synergistically with napabucasin ... |