Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T62748 |
Nampt-IN-9
|
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Nampt-IN-9 (Compound 8) 是一种有效的 NAMPT 抑制剂,具有抗癌作用。Nampt-IN-9 能够用于研究胰腺导管腺癌。 | |||
T18477 |
NAMPT inhibitor-linker 1
|
Others | Others |
NAMPT inhibitor-linker 1, a drug-linker conjugate for ADC, integrates an NAMPT inhibitor (as a payload) with a linker. In the formulation of ADC-3, it pairs with an anti-c-Kit monoclonal antibody, demonstrating strong efficacy against c-Kit expressing cell lines, specifically GIST-T1 and NCI-H526, where it exhibits IC50 values of <3 pM and 9 pM, respectively. |