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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T79622 |
h-NTPDase-IN-3
|
Phosphatase | Metabolism |
h-NTPDase-IN-3 是一种 h-NTPDase 抑制剂,抑制 h-NTPDase1,h-NTPDase2,h-NTPDase3 和 h-NTPDase8。 | |||
T77661 |
h-NTPDase-IN-4
|
Phosphatase | Metabolism |
h-NTPDase-IN-4 是 NTPDase 的泛抑制剂,对 h-NTPDase1, 1h-NTPDase2, h-NTPDase3, h-NTPDase8具有抑制作用,IC50 分别为 3.58 μM , 10.21 μM , 0.13 μM , 13.57 μM 。 | |||
T14320 |
ARL67156 trisodium salt
|
Others | Others |
ARL 67156 is a weak competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12 μM, respectively[1]. ARL67156 trisodium salt is an inhibitor of ecto-ATPase. | |||
T62633 |
NTPDase-IN-3
|
||
NTPDase-IN-3 (Compound 5e) 是一种 NTPDase 抑制剂,IC50值分别为 0.38 μM (NTPDase3), 0.05 μM (NTPDase8), 0.21 μM (NTPDase1), 1.07 μM (NTPDase2)。NTPDase-IN-3 可用于癌症和血栓形成的研究。 | |||
T73644 | ARL67156 trisodium hydrate | ||
ARL67156 (FPL 67156) trisodium hydrate 是一种ecto-ATPase 抑制剂。ARL67156 trisodium hydrate 是竞争性 NTPDase1 (CD39),NTPDase3 和 NPP1 抑制剂,Ki 分别为 11,18 和 12 μM。ARL67156 trisodium hydrate 可用于钙化性主动脉瓣疾病、哮喘等疾病的研究。 | |||
T79623 | h-NTPDase-IN-5 | Phosphatase | Metabolism |
h-NTPDase-IN-5(化合物3b)是一种NTPDase的泛抑制剂,其IC50s对于h-NTPDase1为1.10 μM,h-NTPDase2为44.73 μM,h-NTPDase3为26.14 μM,h-NTPDase8为0.32 μM。 | |||
T12519 |
Sodium metatungstate
POM-1,聚钨酸钠,Sodium polyoxotungstate |
Phosphatase | Metabolism |
Sodium metatungstate (Sodium polyoxotungstate) 是一种外核苷三磷酸二磷酸水解酶抑制剂,能够抑制 ATP 的分解,并阻断中枢突触传递,这是独立于抑制 NTPDase 而发挥作用的。 | |||
T79491 |
h-NTPDase-IN-1
|
Phosphatase | Metabolism |
h-NTPDase-IN-1 (Compound 3i) 是一种针对 h-NTPDase 的抑制剂,对 h-NTPDase1 和 h-NTPDase3 的抑制作用表现在 IC50 值分别为 2.88 μM 和 0.72 μM。该化合物在血栓、炎症、糖尿病及癌症研究领域有潜在应用。 | |||
T73645 |
ARL67156 triethylamine
|
||
ARL67156 (FPL 67156) triethylamine 是一种ecto-ATPase 抑制剂。ARL67156 triethylamine 是竞争性 NTPDase1 (CD39),NTPDase3 和 NPP1 抑制剂,Ki 分别为 11,18 和 12 μM。ARL67156 triethylamine 可用于钙化性主动脉瓣疾病、哮喘等疾病的研究。 | |||
T79607 |
h-NTPDase-IN-2
hNTPDase-IN-2 |
Phosphatase | Metabolism |
h-NTPDase-IN-2 是一种广谱 NTPDase 抑制剂,对多种 h-NTPDas 亚型都具有抑制作用。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03284 |
CD39 Protein, Rat, Recombinant (E. coli, His)
Entpd1,ATP-DPH,Ecto-ATP diphosphohydrolase 1 |
Rat | E. coli |
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. | |||
TMPH-03283 |
CD39 Protein, Rat, Recombinant (His)
ATP diphosphohydrolase,Entpd1,Nucleoside triphospha... |
Rat | Baculovirus Insect Cells |
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. |